Rapoport H, Waterhouse A L, Thompson C M, O'Connell J F
Environ Health Perspect. 1986 Aug;67:41-5. doi: 10.1289/ehp.866741.
The imidazoquinoline and imidazoquinoxaline food mutagens found in cooked meat are being synthesized by unambiguous methods that allow for the preparation of sufficient quantities of material for biological studies. These methods avoid difficult separations of regioisomeric mixtures of products and are designed to allow incorporation of specific high level tritium labeling.
在熟肉中发现的咪唑喹啉和咪唑喹喔啉类食品诱变剂正通过明确的方法进行合成，这些方法能够制备出足够数量的材料用于生物学研究。这些方法避免了产物区域异构体混合物的艰难分离，并且设计用于掺入特定的高剂量氚标记。
