Górski J, Hood D, Kaciuba-Uściłko H, Terjung R L
Eur J Appl Physiol Occup Physiol. 1986;55(4):390-4. doi: 10.1007/BF00422738.
Effects of muscle stimulation were studied in the perfused hindleg of late pregnant and age-matched control rats. Muscle stimulation increased tissue glucose uptake in both groups with a tendency towards higher values in the pregnant rats. The stimulation-induced lactate production was markedly larger in pregnant than in control rats. In the pregnant rats muscle tension output decreased more rapidly and vascular resistance was greater than in non-pregnant group. The decline of tension, accompanied by the enhanced lactate production of contracting muscles, may suggest a reduced muscle oxidative potential in late pregnancy and/or delayed adaptation of the local blood flow. The greater vascular resistance found during muscle stimulation in pregnant animals might have been due to the persistent local action of estrogens. The data obtained indicate that pregnancy modifies skeletal muscle function during stimulation in situ.
在晚期妊娠大鼠和年龄匹配的对照大鼠的灌注后肢中研究了肌肉刺激的作用。两组中肌肉刺激均增加了组织葡萄糖摄取，妊娠大鼠的值有更高的趋势。刺激诱导的乳酸生成在妊娠大鼠中明显大于对照大鼠。妊娠大鼠的肌肉张力输出下降更快，血管阻力大于未妊娠组。张力的下降，伴随着收缩肌肉乳酸生成的增加，可能表明妊娠晚期肌肉氧化潜能降低和/或局部血流适应性延迟。妊娠动物在肌肉刺激期间发现的更大血管阻力可能是由于雌激素的持续局部作用。获得的数据表明，妊娠会改变原位刺激期间的骨骼肌功能。
