Faculdade Ciências Médicas de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Escola de Saúde, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
BMC Palliat Care. 2023 Aug 15;22(1):116. doi: 10.1186/s12904-023-01233-1.
This study aimed to evaluate the risk and protective factors associated with anxiety and depression symptoms in cancer patients at an advanced stage of cancer.
A cross-sectional study was conducted on patients with advanced cancer who were receiving palliative care. Cancer patients aged 18 years or older, with preserved cognitive function who completed the questionnaires were eligible. The questionnaires of Hospital Anxiety and Depression Scale (HADS) and health related of quality of life questionnaire; the European Organization for Research and Treatment of Cancer (EORTC-C30) were applied. Outcome variables were the depression and anxiety symptoms of cancer patients under palliative care, according to the answers to the 14 items that make up the HADS Scale. The analysis used the R software, version 4.2.0.
Seventy cancer patients with advanced cancer were included. The colon was the most common neoplastic diagnostic (20%), followed by breast (12.9%) and lung (10%). The prevalence of depression was 44.3%, 25.7% anxiety and 52.9% had both symptoms. Patients with a high level of functionality had a lower chance of anxiety (OR = 0.80;p = 0.025), depression (OR = 0.82; p = 0.007), and anxiety and depression (OR = 0.82p = 0.008). We observed a lower chance of depression and depression/anxiety who showed a high level of Overall Performance. Three symptoms increased the chance of depression/anxiety: nausea/vomiting (p = 0.019), fatigue (0.031), loss of appetite (0.048).
This study found high prevalence of anxiety and depression.Better quality of life and functionality were negatively associated with these outcomes. Examining the patient's functions will assist the clinician in alleviating symptoms of anxiety and depression, giving cancer patients in palliative care more dignity.
Not applicable.
本研究旨在评估晚期癌症患者焦虑和抑郁症状的相关风险和保护因素。
对接受姑息治疗的晚期癌症患者进行了一项横断面研究。年龄在 18 岁及以上、认知功能正常、完成问卷的癌症患者符合条件。应用了医院焦虑和抑郁量表（HADS）和健康相关生活质量问卷；欧洲癌症研究与治疗组织（EORTC-C30）。根据 HADS 量表的 14 个组成部分的答案，姑息治疗下癌症患者的抑郁和焦虑症状为结局变量。分析使用了 R 软件，版本 4.2.0。
共纳入 70 例晚期癌症患者。最常见的肿瘤诊断是结肠癌（20%），其次是乳腺癌（12.9%）和肺癌（10%）。抑郁的患病率为 44.3%，焦虑为 25.7%，两者兼有为 52.9%。功能水平较高的患者发生焦虑的可能性较低（OR=0.80;p=0.025）、抑郁（OR=0.82;p=0.007）和焦虑和抑郁（OR=0.82p=0.008）。我们观察到，总体表现水平较高的患者发生抑郁和抑郁/焦虑的可能性较低。有三种症状会增加发生抑郁/焦虑的几率：恶心/呕吐（p=0.019）、疲劳（0.031）、食欲不振（0.048）。
本研究发现焦虑和抑郁的患病率较高。更好的生活质量和功能与这些结果呈负相关。检查患者的功能将有助于临床医生缓解焦虑和抑郁症状，为姑息治疗中的癌症患者带来更多尊严。
不适用。
