Xu Wen, Yu Cong, Le Yijun, Zhang Jianzhong
Department of Dermatology, People's Hospital of Peking University, Beijing, People's Republic of China.
Musculoskeletal Tumor Center, People's Hospital of Peking University, Beijing, People's Republic of China.
Clin Cosmet Investig Dermatol. 2022 Oct 7;15:2153-2157. doi: 10.2147/CCID.S387014. eCollection 2022.
Wolf's isotopic response (WIR) refers to the occurrence of a new skin disease at the exact site of an unrelated skin disease that had previously healed, often subsequent to virus infection. Secondary cutaneous diseases that are frequently observed in WIR include granulomatous reactions, dysimmune reactions, malignancies, and infections. However, secondary chronic graft-versus-host disease (GVHD) is rare. We describe a patient with lichen sclerosus-like GVHD who developed lichen planus-like GVHD lesions secondary to herpes zoster infection.
沃尔夫同位素反应（WIR）是指在先前已愈合的无关皮肤病的确切部位出现一种新的皮肤病，通常发生在病毒感染之后。在WIR中经常观察到的继发性皮肤病包括肉芽肿反应、免疫失调反应、恶性肿瘤和感染。然而，继发性慢性移植物抗宿主病（GVHD）很少见。我们描述了一名患有硬化性苔藓样GVHD的患者，该患者在带状疱疹感染后出现了扁平苔藓样GVHD病变。
