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癌症患者的安乐死医疗协助。

Medical Assistance in Dying in Patients With Cancer.

机构信息

Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.

Department of Medical Oncology, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

JCO Oncol Pract. 2023 Sep;19(9):819-827. doi: 10.1200/OP.22.00615. Epub 2023 Aug 15.

Abstract

PURPOSE

Medical assistance in dying (MAiD) was legalized in Canada in 2016. To date, patients with cancer account for 69% of MAiD deaths, yet little information is available about these patients. We reviewed disease and treatment characteristics of patients with cancer who underwent MAiD to better understand this population and identify gaps in our current system of care.

MATERIALS AND METHODS

Patients with cancer who underwent MAiD through the Champlain Regional MAiD Network from June 2016 to November 2020 were reviewed. Baseline demographic, diagnostic, and treatment details were collected by retrospective review.

RESULTS

During the study period, 255 patients with cancer underwent MAiD. At the time of MAiD, 201 patients (79%) had metastatic disease. Most prevalent solid organ tumors were gastrointestinal (30%), lung (18%) and genitourinary (14%). MAiD was primarily provided in the home (48%) or an acute inpatient facility (40%). One hundred eighty-nine (74%) patients were evaluated by medical oncology, 23 by gynecology oncology (9%), 11 by hematology oncology (4%), and 177 (69%) by radiation oncology. One hundred fifty-eight (62%) patients were not seen by oncology specialists in the 30 days prior to MAiD. One hundred fifty-nine patients (62%) had at least one line of systemic therapy, 138 patients (54%) received radiotherapy, and 61 patients (24%) did not receive cancer-directed treatment. Palliative care assessed at least 213 patients (84%). Common reasons for pursuing MaiD included disease-related symptoms (33%), fear of future suffering or disability (19%), and the ability to control the time and manner of death (17%). In 36% of cases, the reason was not documented.

CONCLUSION

Although formal oncology consultation is not required before MAiD, with an ever-increasing number of novel cancer therapies, oncologists, cancer centers, and MAiD providers should consider collaborating to ensure a streamlined assessment process for patients.

摘要

目的

医疗协助死亡(MAiD)于 2016 年在加拿大合法化。迄今为止,癌症患者占 MAiD 死亡人数的 69%,但关于这些患者的信息却很少。我们回顾了接受 MAiD 的癌症患者的疾病和治疗特征,以更好地了解这一人群,并确定我们当前护理系统中的差距。

材料和方法

回顾了 2016 年 6 月至 2020 年 11 月期间通过尚普兰地区 MAiD 网络接受 MAiD 的癌症患者。通过回顾性审查收集了基线人口统计学、诊断和治疗细节。

结果

在研究期间,255 名癌症患者接受了 MAiD。在 MAiD 时,201 名患者(79%)患有转移性疾病。最常见的实体器官肿瘤是胃肠道(30%)、肺部(18%)和泌尿生殖系统(14%)。MAiD 主要在家庭(48%)或急性住院设施(40%)中进行。189 名(74%)患者由肿瘤内科医生评估,23 名由妇科肿瘤医生评估(9%),11 名由血液肿瘤科医生评估(4%),177 名(69%)由放射肿瘤科医生评估。在 MAiD 前 30 天,158 名(62%)患者未接受肿瘤专家的治疗。159 名(62%)患者至少接受过一线系统治疗,138 名(54%)患者接受过放疗,61 名(24%)患者未接受癌症靶向治疗。至少有 213 名(84%)患者接受了姑息治疗评估。寻求 MAiD 的常见原因包括疾病相关症状(33%)、对未来痛苦或残疾的恐惧(19%)以及能够控制死亡时间和方式(17%)。在 36%的病例中,原因未记录。

结论

尽管在进行 MAiD 之前不需要进行正式的肿瘤学咨询,但随着越来越多的新型癌症治疗方法的出现,肿瘤学家、癌症中心和 MAiD 提供者应考虑合作,以确保为患者提供简化的评估流程。

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