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Human cochlear diffusion from the cerebrospinal fluid space with gadolinium contrast.

作者信息

Totten Douglas J, Booth Kevin T A, Mosier Kristine M, Cumpston Evan C, Whitted Cody, Okechuku Vanessa, Koontz Nicholas A, Nelson Rick F

机构信息

Department of Otolaryngology, Head & Neck Surgery, Indiana University, Indianapolis. IN 46202, USA.

Department of Otolaryngology, Head & Neck Surgery, Indiana University, Indianapolis. IN 46202, USA; Department of Medical & Molecular Genetics, Indiana University, Indianapolis, IN 46202, USA.

出版信息

Mol Ther. 2023 Sep 6;31(9):2566-2569. doi: 10.1016/j.ymthe.2023.08.001. Epub 2023 Aug 15.

DOI:10.1016/j.ymthe.2023.08.001
PMID:37582360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10492018/
Abstract
摘要

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Development and evaluation of helper dependent adenoviral vectors for inner ear gene delivery.辅助依赖性腺相关病毒载体的构建及其在内耳基因治疗中的应用。
Hear Res. 2023 Aug;435:108819. doi: 10.1016/j.heares.2023.108819. Epub 2023 May 26.
3
Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F.迷你 PCDH15 基因治疗挽救 1F 型 Usher 综合征小鼠模型的听力。
Nat Commun. 2023 Apr 26;14(1):2400. doi: 10.1038/s41467-023-38038-y.
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Immune responses in the mammalian inner ear and their implications for AAV-mediated inner ear gene therapy.哺乳动物内耳中的免疫反应及其对腺相关病毒介导的内耳基因治疗的影响。
Hear Res. 2023 May;432:108735. doi: 10.1016/j.heares.2023.108735. Epub 2023 Mar 11.
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