Bezpalko Lyudmyla, Filipskiy Andriy
Plastic and Aesthetic Surgery Department, Clinical Hospital of Lviv Railway, Lviv, Ukraine.
Radiology Department, Postgraduate Faculty, Danylo Halytsky Lviv National Medical University, Revive Aesthetic Medicine Clinic, Lviv, Ukraine.
Clin Cosmet Investig Dermatol. 2023 Aug 10;16:2175-2183. doi: 10.2147/CCID.S402409. eCollection 2023.
Nowadays patients want to get an immediate result from skin rejuvenation techniques without sign of injections and consequent limitations in social life. Therefore, the least traumatic, more effective, and longer lasting treatment approach for skin quality improvement should be favored.
Assess skin quality outcomes by clinical examination and self-reporting in patients treated with two non-crosslinked hyaluronic acid (HA) products, injected by cannula. Investigate the skin thickness and the longevity of dermal fillers in soft tissues by ultrasound examination.
Fifteen female patients (mean age 41 years) were selected for injection with two non-crosslinked HA products (one for each hemiface and hemi neck). Subdermal injections were performed bilaterally and the retrograde linear fanning technique with a 25G 50 mm cannula from three entry points was used. An ultrasound examination of the skin layers thickness was carried out before the procedure and every 6-7 days up to three weeks, when patients skin quality improvement was assessed by GAIS (Global Aesthetic Improvement Scale) and patients asked about their satisfaction level.
On the right hemiface, the use of the non-crosslinked HA-product with lidocaine was not associated with pain in the sites of injection. On both face sides, the signs of bruising or edema were minor and not associated with downtime or social life limitation after the procedure. After three weeks, despite both injected products could not be detected by ultrasound technique, signs of skin stimulation and skin layers hydration were still observed: The dermis became thicker on both hemifaces while the epidermis became thinner but showed more pronounced radiance and densification effect on the right hemiface.
Subdermal injections of non-crosslinked HA "skin boosters" could be a good option for minimal traumatic and effective 3-week lasting skin quality improvement.
如今，患者希望通过皮肤年轻化技术立即看到效果，且没有注射痕迹以及随之而来的社交生活限制。因此，应优先选择创伤最小、效果更显著且持久的改善皮肤质量的治疗方法。
通过临床检查和自我报告评估使用两种非交联透明质酸（HA）产品经套管注射治疗的患者的皮肤质量结果。通过超声检查研究软组织中真皮填充剂的皮肤厚度和持久性。
选择15名女性患者（平均年龄41岁），分别在其半侧面部和半侧颈部注射两种非交联HA产品（每侧各一种）。双侧进行皮下注射，采用25G 50mm套管从三个进针点进行逆行线性扇形注射技术。在手术前以及术后每6 - 7天直至三周进行一次皮肤层厚度的超声检查，届时通过GAIS（全球美学改善量表）评估患者的皮肤质量改善情况，并询问患者的满意度。
在右侧半侧面部，使用含利多卡因的非交联HA产品注射部位未出现疼痛。在面部两侧，瘀伤或水肿迹象轻微，术后未导致停工或社交生活受限。三周后，尽管超声技术无法检测到两种注射产品，但仍观察到皮肤刺激和皮肤层水合的迹象：两侧半侧面部的真皮变厚，而表皮变薄，但右侧半侧面部显示出更明显的光泽和致密化效果。
皮下注射非交联HA“皮肤增强剂”可能是实现微创且有效改善皮肤质量并持续3周的良好选择。
