Şahin Maksut, Cengiz Zeynep Taş, Halidi Ahmed Galip, Aydemir Selahattin
Department of Parasitology, Faculty of Medicine, Van Yüzüncü Yıl University, Van, Türkiye.
Bulanik Vocational School, Mus Alparslan University, Mus, Türkiye.
Iran J Parasitol. 2023 Apr-Jun;18(2):202-210. doi: 10.18502/ijpa.v18i2.13186.
We aimed to determine the frequency and subtype of in diabetic patients.
One hundred and fifty diabetic patients and 100 healthy people without any chronic disease were included in the study. Stool samples were analyzed by native-Lugol, condensation, trichrome staining and PCR methods.
İn 150 patients with diabetes; was detected in 38 (25.3%) by PCR, in 34 (22.7%) by native-Lugol and trichrome staining. In the control group, 14 (14%) out of 100 subjects were positive by PCR, and 10 (10%) were positive by native-Lugol and trichrome staining. In the statistical evaluation, a significant difference was found between gender (P=0.023), age (P=0.045; ≤35 and >35 comparison), duration of diabetes (P=0.04), the HbA1c value (P=0.023; <8 and ≥8 comparison), and positivity. ST1 was determined in 76.9% of patients with diabetes, and ST2 was determined in 23.07%. Considering the 3 methods, positivity was detected in 40 patients (26.7%) in diabetic group and in 14 participants (14%) in the control group (P=0.011).
is a factor to be considered in patients with diabetes. Herein, the most common subtype detected in the patients with diabetes mellitus was ST1, but this result was not considered sufficient to reveal the importance of the subtype factor in the pathogenicity of in patients with diabetes. In this context, there is a need for more comprehensive studies in both diabetic and other immunocompromised patient groups.
我们旨在确定糖尿病患者中[某种物质]的频率和亚型。
150例糖尿病患者和100例无任何慢性病的健康人纳入本研究。粪便样本采用天然卢戈氏碘液染色、浓缩染色、三色染色和聚合酶链反应（PCR）方法进行分析。
在150例糖尿病患者中，PCR检测到38例（25.3%）[某种物质]呈阳性，天然卢戈氏碘液染色和三色染色检测到34例（22.7%）呈阳性。在对照组中，100名受试者中有14例（14%）PCR检测呈阳性，10例（10%）天然卢戈氏碘液染色和三色染色检测呈阳性。在统计学评估中，发现性别（P = 0.023）、年龄（P = 0.045；≤35岁与>35岁比较）、糖尿病病程（P = 0.04）、糖化血红蛋白（HbA1c）值（P = 0.023；<8与≥8比较）与[某种物质]阳性之间存在显著差异。糖尿病患者中76.9%确定为ST1型，23.07%确定为ST2型。综合三种方法，糖尿病组40例患者（26.7%）检测到[某种物质]阳性，对照组14例参与者（14%）检测到阳性（P = 0.011）。
[某种物质]是糖尿病患者需要考虑的一个因素。在此，糖尿病患者中检测到的最常见亚型是ST1型，但该结果不足以揭示亚型因素在糖尿病患者[某种物质]致病性中的重要性。在这种情况下，需要对糖尿病患者和其他免疫功能低下患者群体进行更全面的研究。
