Aydin Ozlem Celik, Aydin Sonay, Guney Hakkı Zafer
Department of Medical Pharmacology, Gazi University Faculty of Medicine, Ankara 06500, Turkey.
World J Clin Cases. 2023 Jul 16;11(20):4865-4873. doi: 10.12998/wjcc.v11.i20.4865.
Pharmacovigilance (PV) is the activities and scientific studies conducted to detect, evaluate, understand or prevent adverse reactions and other drug-related problems.
To define the awareness and experiences of the clinicians on PV and adverse drug reactions (ADRs) in Turkey.
The study was cross-sectional and analytical. Data were obtained through a questionnaire. The questionnaire was sent e-mail. The survey was sent to 2030 physicians and 670 participated.
The most appropriate definition of PV was correctly defined by 53.9% of the participants. The most important goal of PV was correctly defined by 54.9% of the participants, and 27.3% of the participants were aware of the Turkish Pharmacovigilance Center. Nonsurgical physicians had better PV knowledge than surgical physicians. A total of 80.9% of the physicians who encountered ADRs, filled in the ADR notification form, and 8.8% received training on how to fill in the form. PV knowledge of the clinicians was not sufficient. Although half of the physicians encountered ADRs, the rates of seeing and filling in the ADR form were low.
Few of the physicians followed the current information about PV. The results provide more comprehensive data on PV practices and ADR reporting at a national level.
药物警戒（PV）是为检测、评估、理解或预防不良反应及其他与药物相关问题而开展的活动和科学研究。
明确土耳其临床医生对药物警戒和药物不良反应（ADR）的认知及经验。
本研究为横断面分析研究。通过问卷调查获取数据。问卷通过电子邮件发送。共向2030名医生发送了调查问卷，670人参与了调查。
53.9%的参与者正确定义了药物警戒的最合适定义。54.9%的参与者正确定义了药物警戒的最重要目标，27.3%的参与者知晓土耳其药物警戒中心。非外科医生的药物警戒知识比外科医生更好。总共80.9%遇到药物不良反应的医生填写了药物不良反应报告表，8.8%接受过如何填写表格的培训。临床医生的药物警戒知识不足。尽管一半的医生遇到过药物不良反应，但填写药物不良反应表格的比例较低。
很少有医生了解药物警戒的当前信息。研究结果为国家层面的药物警戒实践和药物不良反应报告提供了更全面的数据。
