Manne Sharon L, Hudson Shawna V, Preacher Kristopher J, Imanguli Matin, Pesanelli Morgan, Frederick Sara, Singh Neetu, Schaefer Alexis, Van Cleave Janet H
Rutgers Cancer Institute of New Jersey, 120 Albany St, 8th Floor, New Brunswick, NJ, 08901, USA.
Institute for Health, Health Care Policy and Aging Research, Robert Wood Johnson Medical School, 112 Paterson St, New Brunswick, NJ, 08901, USA.
J Cancer Surviv. 2025 Feb;19(1):66-77. doi: 10.1007/s11764-023-01449-3. Epub 2023 Aug 16.
Fear of recurrence (FoR) is a prevalent and difficult experience among cancer patients. Most research has focused on FoR among breast cancer patients, with less attention paid to characterizing levels and correlates of FoR among oral and oropharyngeal cancer survivors. The purpose was to characterize FoR with a measure assessing both global fears and the nature of specific worries as well as evaluate the role of sociodemographic and clinical factors, survivorship care transition practices, lifestyle factors, and depressive symptoms in FoR.
Three hundred eighty-nine oral and oropharyngeal survivors recruited from two cancer registries completed a survey assessing demographics, cancer treatment, symptoms, alcohol and tobacco use, survivorship care practices, depression, and FoR.
Forty percent reported elevated global FoR, with similar percentages for death (46%) and health worries (40.3%). Younger, female survivors and survivors experiencing more physical and depressive symptoms reported more global fears and specific fears about the impact of recurrence on roles, health, and identity, and fears about death. Depression accounted for a large percent of the variance. Lower income was associated with more role and identity/sexuality worries, and financial hardship was associated with more role worries.
FoR is a relatively common experience for oral and oropharyngeal cancer survivors. Many of its correlates are modifiable factors that could be addressed with multifocal, tailored survivorship care interventions.
Assessing and addressing depressive symptoms, financial concerns, expected physical symptoms in the first several years of survivorship may impact FoR among oral and oropharyngeal cancer survivors.
癌症患者中，对复发的恐惧（FoR）是一种普遍且痛苦的经历。大多数研究聚焦于乳腺癌患者的FoR，而对口腔和口咽癌幸存者FoR水平及其相关因素的特征描述关注较少。本研究旨在通过一项评估整体恐惧及特定担忧性质的测量方法来描述FoR，并评估社会人口学和临床因素、生存护理过渡措施、生活方式因素及抑郁症状在FoR中的作用。
从两个癌症登记处招募的389名口腔和口咽癌幸存者完成了一项调查，内容包括人口统计学、癌症治疗、症状、烟酒使用、生存护理措施、抑郁和FoR。
40%的人报告整体FoR升高，对死亡（46%）和健康担忧（40.3%）的比例相似。更年轻的女性幸存者以及经历更多身体和抑郁症状的幸存者报告了更多的整体恐惧，以及对复发对角色、健康和身份的影响的特定恐惧，还有对死亡的恐惧。抑郁占差异的很大比例。低收入与更多的角色及身份/性取向担忧相关，经济困难与更多的角色担忧相关。
FoR在口腔和口咽癌幸存者中是相对常见的经历。其许多相关因素是可改变的因素，可通过多方面、量身定制的生存护理干预措施来解决。
评估和解决抑郁症状、经济问题以及生存头几年预期的身体症状可能会影响口腔和口咽癌幸存者的FoR。
