Chair for Animal Nutrition and Dietetics, Department of Veterinary Sciences, Faculty of Veterinary Medicine, LMU München, München, Germany.
Chair of Bacteriology and Mycology, Institute of Infectious Diseases and Zoonoses, Department of Veterinary Sciences, Faculty of Veterinary Medicine, LMU München, München, Germany.
PLoS One. 2023 Aug 16;18(8):e0290145. doi: 10.1371/journal.pone.0290145. eCollection 2023.
Data on mineral digestibility is key to understand mineral homeostasis and refine the recommendations for the dietary intake of these nutrients. In farm animals and pets, there is plenty of data on mineral digestibility and influencing factors. In laboratory mice, however, there is a lack of information on mineral digestibility under maintenance conditions, although this should be the basis for studies on mineral homeostasis under experimental conditions. The aim of the present study was to analyse data on intake, faecal excretion, and apparent digestibility of calcium, phosphorus, sodium, potassium, and magnesium in C57BL/6J mice fed different maintenance diets with varying voluntary dry matter intake. Lucas-tests were used to quantify true digestibility and describe correlations between dietary intake and excretion/absorption of the nutrients. Calcium, phosphorus, and magnesium showed a linear correlation between intake and faecal excretion (R2: 0.77, 0.93 and 0.91, respectively). Intake and apparently digested amounts of sodium and potassium were correlated linearly (R2: 0.86 and 0.98, respectively). These data show that intake is the major determinant of absorption in the minerals listed above. Faecal calcium and phosphorus excretion were correlated as well (R2 = 0.75).
有关矿物质消化率的数据对于了解矿物质体内平衡和完善这些营养素的膳食摄入量建议至关重要。在农场动物和宠物中，有大量关于矿物质消化率及其影响因素的数据。然而，在实验条件下研究矿物质体内平衡时，维持状态下的矿物质消化率的信息在实验用的小鼠中却很缺乏，尽管这应该是研究矿物质体内平衡的基础。本研究的目的是分析在不同维持饮食下，具有不同自愿干物质摄入量的 C57BL/6J 小鼠的钙、磷、钠、钾和镁的摄入量、粪便排泄量和表观消化率的数据。Lucas 检验用于量化真消化率，并描述营养素的饮食摄入与排泄/吸收之间的相关性。钙、磷和镁的摄入量与粪便排泄量之间呈线性相关（R2：分别为 0.77、0.93 和 0.91）。钠和钾的摄入量与表观消化量呈线性相关（R2：分别为 0.86 和 0.98）。这些数据表明，上述矿物质的吸收主要取决于摄入量。粪便钙和磷的排泄也呈相关（R2 = 0.75）。
