Wang Haixia, Oliveira-Garcia Ely, Boevink Petra C, Talbot Nicholas J, Birch Paul R J, Valent Barbara
State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest Agriculture & Forestry University, Yangling, Shanxi 712100, China; Division of Plant Science, School of Life Sciences, University of Dundee, James Hutton Institute, Errol Road, Invergowrie, Dundee DD2 5DA, UK.
Department of Plant Pathology, Kansas State University, Manhattan, KS 66506, USA; Department of Plant Pathology and Crop Physiology, Louisiana State University Agricultural Center, Baton Rouge, LA 70803, USA.
Trends Plant Sci. 2023 Nov;28(11):1214-1217. doi: 10.1016/j.tplants.2023.07.015. Epub 2023 Aug 14.
Recent findings demonstrate that cytoplasmic effectors from fungal and oomycete pathogens enter plant cells via clathrin-mediated endocytosis (CME). This raises several questions: Does effector secretion pathway facilitate host uptake? How is CME triggered in host cells? How are the effectors released from endosomal compartments to reach diverse subcellular destinations?
最近的研究结果表明,来自真菌和卵菌病原体的细胞质效应蛋白通过网格蛋白介导的内吞作用(CME)进入植物细胞。这引发了几个问题:效应蛋白分泌途径是否有助于宿主摄取?宿主细胞中的CME是如何触发的?效应蛋白如何从内体区室释放以到达不同的亚细胞目的地?