College of Food Science and Engineering, Qingdao Agricultural University, Qingdao, China.
Qingdao Special Food Research Institute, Qingdao, China.
Crit Rev Food Sci Nutr. 2024 Nov;64(32):12040-12060. doi: 10.1080/10408398.2023.2246554. Epub 2023 Aug 17.
The use of antibiotics had reached a plateau due to antibiotic resistance, overuse, and residue. Bacteriophages have recently attracted considerable attention as alternative biocontrol agents. Here, we provide an up-to-date overview of phage applications in the food industry. We reviewed recently reported phages against ten typical foodborne pathogens, studies of competitive phage-encoded endolysins, and the primary outcomes of phage encapsulation in food packaging and pathogen detection. Furthermore, we identified existing barriers that still need to be addressed and proposed potential solutions to overcome these obstacles in the future.
由于抗生素耐药性、过度使用和残留等问题，抗生素的使用已经达到了一个瓶颈。噬菌体最近作为替代生物防治剂引起了相当大的关注。在这里，我们提供了噬菌体在食品工业中应用的最新概述。我们综述了最近报道的针对十种典型食源性致病菌的噬菌体、竞争噬菌体编码的内溶素的研究，以及噬菌体在食品包装和病原体检测中的封装的主要结果。此外，我们确定了仍然需要解决的现有障碍，并提出了未来克服这些障碍的潜在解决方案。
