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基于机器学习技术的医院法律建设对医患纠纷的预测:外部验证的横断面研究。

Prediction of Medical Disputes Between Health Care Workers and Patients in Terms of Hospital Legal Construction Using Machine Learning Techniques: Externally Validated Cross-Sectional Study.

机构信息

Institute of Medical Information and Library, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Health Commission of Hunan Province, Changsha, China.

出版信息

J Med Internet Res. 2023 Aug 17;25:e46854. doi: 10.2196/46854.

Abstract

BACKGROUND

Medical disputes are a global public health issue that is receiving increasing attention. However, studies investigating the relationship between hospital legal construction and medical disputes are scarce. The development of a multicenter model incorporating machine learning (ML) techniques for the individualized prediction of medical disputes would be beneficial for medical workers.

OBJECTIVE

This study aimed to identify predictors related to medical disputes from the perspective of hospital legal construction and the use of ML techniques to build models for predicting the risk of medical disputes.

METHODS

This study enrolled 38,053 medical workers from 130 tertiary hospitals in Hunan province, China. The participants were randomly divided into a training cohort (34,286/38,053, 90.1%) and an internal validation cohort (3767/38,053, 9.9%). Medical workers from 87 tertiary hospitals in Beijing were included in an external validation cohort (26,285/26,285, 100%). This study used logistic regression and 5 ML techniques: decision tree, random forest, support vector machine, gradient boosting decision tree (GBDT), and deep neural network. In total, 12 metrics, including discrimination and calibration, were used for performance evaluation. A scoring system was developed to select the optimal model. Shapley additive explanations was used to generate the importance coefficients for characteristics. To promote the clinical practice of our proposed optimal model, reclassification of patients was performed, and a web-based app for medical dispute prediction was created, which can be easily accessed by the public.

RESULTS

Medical disputes occurred among 46.06% (17,527/38,053) of the medical workers in Hunan province, China. Among the 26 clinical characteristics, multivariate analysis demonstrated that 18 characteristics were significantly associated with medical disputes, and these characteristics were used for ML model development. Among the ML techniques, GBDT was identified as the optimal model, demonstrating the lowest Brier score (0.205), highest area under the receiver operating characteristic curve (0.738, 95% CI 0.722-0.754), and the largest discrimination slope (0.172) and Youden index (1.355). In addition, it achieved the highest metrics score (63 points), followed by deep neural network (46 points) and random forest (45 points), in the internal validation set. In the external validation set, GBDT still performed comparably, achieving the second highest metrics score (52 points). The high-risk group had more than twice the odds of experiencing medical disputes compared with the low-risk group.

CONCLUSIONS

We established a prediction model to stratify medical workers into different risk groups for encountering medical disputes. Among the 5 ML models, GBDT demonstrated the optimal comprehensive performance and was used to construct the web-based app. Our proposed model can serve as a useful tool for identifying medical workers at high risk of medical disputes. We believe that preventive strategies should be implemented for the high-risk group.

摘要

背景

医疗纠纷是一个全球性的公共卫生问题,越来越受到关注。然而,研究医院法律建设与医疗纠纷之间关系的研究很少。开发一种纳入机器学习(ML)技术的多中心模型,用于个体化预测医疗纠纷,将对医务人员有益。

目的

本研究旨在从医院法律建设的角度识别与医疗纠纷相关的预测因素,并利用 ML 技术构建预测医疗纠纷风险的模型。

方法

本研究纳入了来自中国湖南省 130 家三级医院的 38053 名医务人员。参与者被随机分为训练队列(34286/38053,90.1%)和内部验证队列(3767/38053,9.9%)。来自北京 87 家三级医院的医务人员被纳入外部验证队列(26285/26285,100%)。本研究使用逻辑回归和 5 种 ML 技术:决策树、随机森林、支持向量机、梯度提升决策树(GBDT)和深度神经网络。总共使用了 12 个指标,包括区分度和校准度,用于性能评估。开发了一个评分系统来选择最佳模型。Shapley 加性解释用于生成特征的重要性系数。为了促进我们提出的最佳模型在临床实践中的应用,对患者进行了重新分类,并创建了一个用于医疗纠纷预测的基于网络的应用程序,公众可以轻松访问该应用程序。

结果

在中国湖南省,46.06%(17527/38053)的医务人员发生了医疗纠纷。在 26 个临床特征中,多变量分析表明,18 个特征与医疗纠纷显著相关,这些特征被用于 ML 模型的开发。在 ML 技术中,GBDT 被确定为最佳模型,具有最低的 Brier 得分(0.205)、最高的受试者工作特征曲线下面积(0.738,95%CI 0.722-0.754)和最大的区分斜率(0.172)和 Youden 指数(1.355)。此外,它在内部验证集的指标得分最高(63 分),其次是深度神经网络(46 分)和随机森林(45 分)。在外部验证集中,GBDT 的表现仍然相当,获得了第二高的指标得分(52 分)。高风险组发生医疗纠纷的几率是低风险组的两倍多。

结论

我们建立了一个预测模型,将医务人员分为不同的风险组,以预测他们是否会遇到医疗纠纷。在 5 种 ML 模型中,GBDT 表现出最佳的综合性能,并被用于构建基于网络的应用程序。我们提出的模型可以作为识别高风险医疗纠纷的有用工具。我们相信应该对高风险组实施预防策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97b4/10472173/04114e9ffaf8/jmir_v25i1e46854_fig1.jpg

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