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检测女性甲状腺功能减退患者的体脂百分比、皮肤电反应和肌肉握力

Examining Body Fat Percentage, Galvanic Skin Response, and Muscle Grip Strength in Female Hypothyroid Patients.

作者信息

A Prashanth, Kothari Ruchi, S Yogesh, Mittal Gaurav, Gheewala Shabbir, Bokariya Pradeep, Palande Amisha, S Devupriya M, Tamrakar Shubhi, Vemparala Sai Shanmukh

机构信息

Physiology, Mahatma Gandhi Institute of Medical Sciences, Wardha, IND.

Research, Rotaract Club of Indian Medicos, Mumbai, IND.

出版信息

Cureus. 2023 Jul 17;15(7):e42023. doi: 10.7759/cureus.42023. eCollection 2023 Jul.

Abstract

Background The thyroid gland is an indispensable organ exerting control over the activity of multiple organ systems including the autonomic nervous system. This study attempted to monitor the variations in autonomic function parameters such as galvanic skin response (GSR) and muscle grip strength (HGS) in conjunction with changes in body fat percentage (BFP). Methodology This case-control study was conducted among 40 female hypothyroid patients as cases and 40 age-matched female healthy volunteers as controls. Anthropometric data were collected using standard techniques. GSR and HGS were measured using Equivital Sensory Electronic Module and Grip Force Transducer, respectively. Data extraction and analysis were done using the LabChart software. Results The mean age of the 40 female hypothyroid patients was 30.14 ± 5.91 years, whereas the mean age of the female controls was 29.37 ± 6.59 years. The waist circumference of cases was 85.81 ± 10.39 cm while that of controls was 80.90 ± 11.18 cm. The BFP of cases was 35.38% ± 6.74% while that of controls was 31.72% ± 5.63%. The GSR amplitude showed a significant difference between hypothyroid and healthy volunteers with values of 1.34 ± 1.14 μS and 2.40 ± 1.86 μS, respectively. The HGS indices showed no significant difference between the two groups. A statistically negative correlation was noted between BFP and GSR amplitude (-0.32), whereas a positive correlation was noted between BFP and mean handgrip strength (0.31) in hypothyroid patients. Conclusions The changes in BFP and autonomic function through GSR and HGS were evaluated in female hypothyroid patients with respect to healthy females. The interrelationship between anthropometry and autonomic function was also explored in this study. The findings of this study can augment prognosis in patients and ensure timely corrective treatment for improving quality of life.

摘要

背景 甲状腺是一个不可或缺的器官,对包括自主神经系统在内的多个器官系统的活动发挥着控制作用。本研究试图监测诸如皮肤电反应(GSR)和握力(HGS)等自主功能参数的变化,并结合体脂百分比(BFP)的变化进行研究。方法 本病例对照研究选取40名女性甲状腺功能减退患者作为病例组,40名年龄匹配的女性健康志愿者作为对照组。使用标准技术收集人体测量数据。分别使用Equivital感觉电子模块和握力传感器测量GSR和HGS。使用LabChart软件进行数据提取和分析。结果 40名女性甲状腺功能减退患者的平均年龄为30.14±5.91岁,而女性对照组的平均年龄为29.37±6.59岁。病例组的腰围为85.81±10.39厘米,而对照组的腰围为80.90±11.18厘米。病例组的BFP为35.38%±6.74%,而对照组的BFP为31.72%±5.63%。甲状腺功能减退患者和健康志愿者之间的GSR振幅存在显著差异,分别为1.34±1.14微西门子和2.40±1.86微西门子。两组之间的HGS指数无显著差异。在甲状腺功能减退患者中,BFP与GSR振幅之间存在统计学上的负相关(-0.32),而BFP与平均握力之间存在正相关(0.31)。结论 针对健康女性,评估了女性甲状腺功能减退患者BFP和通过GSR及HGS体现的自主功能变化。本研究还探讨了人体测量学与自主功能之间的相互关系。本研究结果可改善患者预后,并确保及时进行纠正治疗以提高生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82c6/10431213/ffcd01557214/cureus-0015-00000042023-i01.jpg

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