Nakajima Shohei, Setoyama Ami, Sato Iori, Fukuchi Tomoko, Tanaka Harumi, Inoue Masami, Watanabe Kentaro, Koh Katsuyoshi, Takita Junko, Tokuyama Mika, Watanabe Kenichiro, Kamibeppu Kiyoko
Department of Family Nursing, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Department of Nursing, Osaka Women's and Children's Hospital, Osaka, Japan.
Blood Cell Ther. 2019 Jul 18;2(3):39-49. doi: 10.31547/bct-2018-010. eCollection 2019 Aug 1.
The purposes of this study were (1) to describe the levels of anxiety and depressive symptoms in parents of children undergoing hematopoietic stem cell transplantation (HSCT) before (Time 1 [T1]) and one month after transplantation (Time 2 [T2]), and (2) to identify the pre-HSCT factors that predict anxiety and depressive symptoms in fathers and mothers one month after transplantation.
A prospective quantitative study was conducted at four children's hospitals between June 2015 and September 2016 using self-administered questionnaires and medical records. Parents from 23 families, including 19 fathers and 23 mothers, completed the Hospital Anxiety and Depression Scale (cutoff score: 8) and provided information regarding their stress appraisal, coping strategies, family functioning, demographic characteristics, and children's health-related quality of life. Hierarchical multiple regression analysis was performed to identify the variables that predicted T2 paternal and maternal anxiety and depressive symptoms.
Among the parents, 15 fathers (79%) and 11 mothers (48%) reported anxiety symptoms, and 13 fathers (68%) and 9 mothers (39%) reported depressive symptoms above the cutoff level for clinical relevance at T1. Similarly, 11 fathers (58%) and 6 mothers (26%) reported anxiety symptoms, and 10 fathers (53%) and 9 mothers (39%) reported depressive symptoms above the cutoff level at T2. Overall, parents' anxiety and depressive symptoms did not differ significantly between T1 and T2. For fathers, both T1 depressive symptoms and the understanding of their children's medical situation through communication with other parents and consultation with medical staff predicted T2 paternal depressive symptoms. For mothers, T1 maternal anxiety symptoms and marital satisfaction predicted T2 anxiety symptoms.
The medical staff should understand that parents of children undergoing HSCT experience considerable psychological distress throughout the treatment process, and therefore, they should adopt unique approaches to reduce such distress.
本研究的目的是：（1）描述造血干细胞移植（HSCT）患儿家长在移植前（时间1 [T1]）和移植后1个月（时间2 [T2]）的焦虑和抑郁症状水平；（2）确定移植前能预测移植后1个月父亲和母亲焦虑和抑郁症状的因素。
2015年6月至2016年9月在四家儿童医院进行了一项前瞻性定量研究，采用自填问卷和病历资料。来自23个家庭的家长，包括19名父亲和23名母亲，完成了医院焦虑抑郁量表（临界值：8分），并提供了有关其压力评估、应对策略、家庭功能、人口统计学特征以及儿童健康相关生活质量的信息。进行分层多元回归分析以确定预测T2期父亲和母亲焦虑及抑郁症状的变量。
在家长中，15名父亲（79%）和11名母亲（48%）在T1期报告有焦虑症状，13名父亲（68%）和9名母亲（39%）报告有高于临床相关临界水平的抑郁症状。同样，11名父亲（58%）和6名母亲（26%）在T2期报告有焦虑症状，10名父亲（53%）和
