School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, P.O. Box 446, Jounieh, Lebanon.
Applied Science Research Center, Applied Science Private University, Amman, Jordan.
BMC Res Notes. 2023 Aug 18;16(1):176. doi: 10.1186/s13104-023-06454-4.
The effects of COVID-19 on the organism are still being investigated, especially after the transformation of this virus from a respiratory disease in its first appearance to a multi-organ disease that can affect nearly all systems and organs including the endocrinological system. The objective of the study was to find an association between COVID-19 infection and new onset type 2 diabetes in Lebanese adults.
A retrospective case-control study (2019-2022) included 200 subjects, 100 cases with new onset diabetes and 100 controls recruited from endocrinology clinics in rural and suburban located regions of Lebanon. Univariate and multivariate logistic regression were performed.
Older age (aOR = 1.07; 95% CI 1.03-1.12), higher BMI (aOR = 1.32; 95% CI 1.17-1.48), having been infected with COVID-19 (aOR = 2.38; 95% CI 1.001-5.68) and having a family history of diabetes (aOR = 11.80; 95% CI 4.23-32.87) were significantly associated with higher odds of having new onset type 2 diabetes after adjusting for multiple risk factors.
In addition to the traditional risk factors for developing type 2 diabetes, a recent COVID-19 infection was associated with the new onset DM in our study. Subsequently screening for diabetes should be strongly recommended for patients post COVID-19 infection.
COVID-19 对机体的影响仍在研究中，尤其是该病毒从最初出现的呼吸道疾病转变为可影响几乎所有系统和器官（包括内分泌系统）的多器官疾病之后。本研究的目的是在黎巴嫩成年人中寻找 COVID-19 感染与 2 型糖尿病发病之间的关联。
这是一项回顾性病例对照研究（2019-2022 年），共纳入 200 名受试者，100 例新发糖尿病患者和 100 例对照来自黎巴嫩农村和郊区的内分泌诊所。进行单变量和多变量逻辑回归分析。
年龄较大（OR = 1.07；95%CI 1.03-1.12）、BMI 较高（OR = 1.32；95%CI 1.17-1.48）、感染过 COVID-19（OR = 2.38；95%CI 1.001-5.68）和有糖尿病家族史（OR = 11.80；95%CI 4.23-32.87）与调整多个危险因素后发生 2 型糖尿病的几率增加显著相关。
除了发生 2 型糖尿病的传统危险因素外，本研究中近期 COVID-19 感染与新发 DM 相关。因此，建议对 COVID-19 感染后的患者进行糖尿病筛查。
