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Editorial: The discovery of bioactive natural products: the isolation and structural elucidation, genome mining, OSMAC strategy, and biotransformation.社论：生物活性天然产物的发现：分离与结构解析、基因组挖掘、OSMAC策略及生物转化
Front Microbiol. 2023 Aug 3;14:1253850. doi: 10.3389/fmicb.2023.1253850. eCollection 2023.
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Genome mining and OSMAC strategies unveil diverse secondary metabolites from the endophytic fungus ZMU-48-1 with antifungal activity.基因组挖掘和OSMAC策略揭示了具有抗真菌活性的内生真菌ZMU-48-1的多种次生代谢产物。
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本文引用的文献

1
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019.天然产物：1981 年 1 月至 2019 年 9 月近四十年来的新药来源
J Nat Prod. 2020 Mar 27;83(3):770-803. doi: 10.1021/acs.jnatprod.9b01285. Epub 2020 Mar 12.
2
From genomics to metabolomics, moving toward an integrated strategy for the discovery of fungal secondary metabolites.从基因组学到代谢组学，朝着发现真菌次生代谢产物的综合策略迈进。
Nat Prod Rep. 2018 Feb 21;35(2):147-173. doi: 10.1039/c7np00032d.
3
Alexander Fleming (1881-1955): Discoverer of penicillin.亚历山大·弗莱明（1881 - 1955）：青霉素的发现者。
Singapore Med J. 2015 Jul;56(7):366-7. doi: 10.11622/smedj.2015105.

Editorial: The discovery of bioactive natural products: the isolation and structural elucidation, genome mining, OSMAC strategy, and biotransformation.

作者信息

Zhang Dewu, Morgan Kalindi, Liu Ling

机构信息

Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Department of Chemistry and Biochemistry, University of Northern British Columbia, Prince George, BC, Canada.

出版信息

Front Microbiol. 2023 Aug 3;14:1253850. doi: 10.3389/fmicb.2023.1253850. eCollection 2023.

DOI:10.3389/fmicb.2023.1253850
PMID:37601349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10435897/
Abstract
摘要