Peiffer C, Brombal L, Maughan Jones C J, Arfelli F, Astolfo A, Dreossi D, Endrizzi M, Hagen C K, Mazzolani A, Menk R, Rigon L, Olivo A, Munro P R T
Department of Medical Physics and Biomedical Engineering, University College London, Gower Street, WC1E 6BT London, United Kingdom.
Department of Physics, University of Trieste, Via Valerio 2, 34127 Trieste, Italy.
J Phys D Appl Phys. 2023 Nov 9;56(45):45LT02. doi: 10.1088/1361-6463/acee8c. Epub 2023 Aug 18.
X-ray phase contrast imaging (XPCI) methods give access to contrast mechanisms that are based on the refractive properties of matter on top of the absorption coefficient in conventional x-ray imaging. Ultra small angle x-ray scattering (USAXS) is a phase contrast mechanism that arises due to multiple refraction events caused by physical features of a scale below the physical resolution of the used imaging system. USAXS contrast can therefore give insight into subresolution structural information, which is an ongoing research topic in the vast field of different XPCI techniques. In this study, we quantitatively compare the USAXS signal retrieved by the beam tracking XPCI technique with the gold standard of the analyzer based imaging XPCI technique using a synchrotron x-ray source. We find that, provided certain conditions are met, the two methods measure the same quantity.
X射线相衬成像（XPCI）方法能够利用物质的折射特性产生对比度，这是在传统X射线成像吸收系数基础上的一种对比度机制。超小角X射线散射（USAXS）是一种相衬机制，它是由低于所用成像系统物理分辨率尺度的物理特征引起的多次折射事件产生的。因此，USAXS对比度能够提供关于亚分辨率结构信息的见解，这在不同XPCI技术的广阔领域中是一个正在进行研究的课题。在本研究中，我们使用同步加速器X射线源，将光束跟踪XPCI技术获取的USAXS信号与基于分析仪成像的XPCI技术的金标准进行了定量比较。我们发现，在满足一定条件的情况下，这两种方法测量的是同一个量。
