Pellegrini V D, Tompkins A
J Hand Surg Am. 1986 Sep;11(5):718-24. doi: 10.1016/s0363-5023(86)80019-3.
Two-year follow-up of a subungual keratoacanthoma treated by curettage has shown partial reconstitution of the bony defect in the distal phalanx. Previous recommendations for treatment of this tumor have been divergent, ranging from conservative local excision to aggressive amputation. Review of the 18 cases reported in the literature reveals that 86% of the lesions ultimately treated by curettage did not recur. Two patients with recurrent disease after curettage were cured by eventual conservative amputation. Aggressive ablative surgery as the initial intervention for this benign condition should be discouraged.
对一例采用刮除术治疗的甲下角化棘皮瘤进行的两年随访显示，远端指骨的骨缺损部分得到了重建。此前针对该肿瘤的治疗建议各不相同，从保守的局部切除到激进的截肢手术都有。对文献报道的18例病例进行回顾发现，最终采用刮除术治疗的病变中有86%未复发。两名刮除术后复发的患者最终通过保守截肢治愈。对于这种良性疾病，不应鼓励将激进的切除手术作为初始干预手段。
