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手部创伤手术部位感染的风险,以及 SARS-CoV-2 大流行的影响:一项队列研究。

Risk of surgical site infection in hand trauma, and the impact of the SARS-CoV-2 pandemic: A cohort study.

机构信息

Department of Plastic & Reconstructive Surgery, Stoke Mandeville Hospital, Aylesbury, UK.

Department of Plastic & Reconstructive Surgery, Stoke Mandeville Hospital, Aylesbury, UK; Warwick Clinical Trials Unit, University of Warwick, Coventry, UK.

出版信息

J Plast Reconstr Aesthet Surg. 2021 Nov;74(11):3080-3086. doi: 10.1016/j.bjps.2021.06.016. Epub 2021 Jul 2.

Abstract

BACKGROUND

Despite the ubiquity of hand trauma, there remains insufficient published data to reliably inform these patients of surgical site infection (SSI) risk. We describe the risk of SSI in a single-centre cohort of patients with hand trauma, with an analysis of the impact of the coronavirus disease-2019 (COVID-19) pandemic.

METHODS

Retrospective data collection of consecutive patients who underwent surgery for hand and wrist trauma in a single plastic surgery centre over two, three-month periods. Demographic, injury and operative details, alongside prophylactic antibiotic use, were recorded. Burn injuries and wounds infected at presentation were excluded. Presence of SSI at 30 days (90 days if a surgical implant was used) was assessed.

RESULTS

Overall, 556 patients - 'Pre-COVID-19' (n = 310) and 'During COVID-19' (n = 246) - were included. Risk of SSI was 3.6% in the aggregated cohort. Female patients were more likely to develop an SSI, even when adjusted for their greater prevalence of bite aetiologies (adj OR 2.5; 95% CI, 1.00-6.37 and p < 0.05). The absolute risk of SSI in the 'Pre-COVID-19' group was 2.3% and 5.3% in the 'During COVID-19' group. The relative risk of developing an SSI in the 'During COVID-19' group was 2.34 (95% CI, 0.95-5.78 and p = 0.06). Baseline characteristics were equivalent between the two groups.

CONCLUSION

The risk of SSI in hand trauma is the same as the nationally estimated risk for all surgeries; 3-5%. Changes in presentation and practice associated with the first wave of the COVID-19 pandemic did not appear to alter the risk of SSI in patients undergoing surgery for hand trauma.

摘要

背景

尽管手部创伤很常见,但仍缺乏可靠的发表数据来告知这些患者手术部位感染 (SSI) 的风险。我们描述了在单一中心手部创伤患者队列中 SSI 的风险,并分析了 2019 年冠状病毒病 (COVID-19) 大流行的影响。

方法

回顾性收集在单个整形手术中心连续接受手部和腕部创伤手术的患者数据,记录人口统计学、损伤和手术细节,以及预防性抗生素的使用情况。排除烧伤和就诊时感染的伤口。评估 30 天(如果使用手术植入物则为 90 天)时是否存在 SSI。

结果

总体而言,共有 556 名患者(“COVID-19 前”n=310 名和“COVID-19 期间”n=246 名)被纳入研究。综合队列中 SSI 的风险为 3.6%。即使在调整了咬伤病因的更高发病率后,女性患者发生 SSI 的可能性也更高(调整后的 OR 2.5;95%CI,1.00-6.37,p<0.05)。“COVID-19 前”组 SSI 的绝对风险为 2.3%,“COVID-19 期间”组为 5.3%。“COVID-19 期间”组发生 SSI 的相对风险为 2.34(95%CI,0.95-5.78,p=0.06)。两组的基线特征相当。

结论

手部创伤的 SSI 风险与全国所有手术的估计风险相同;3-5%。与 COVID-19 大流行第一波相关的就诊和治疗方式的变化似乎并未改变接受手部创伤手术患者的 SSI 风险。

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