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互联网提供的认知行为疗法为睡眠障碍高危轮班工人改善睡眠的应用效果:单臂、非随机试验。

Effect of an Internet-Delivered Cognitive Behavioral Therapy-Based Sleep Improvement App for Shift Workers at High Risk of Sleep Disorder: Single-Arm, Nonrandomized Trial.

机构信息

Emergency and Critical Care Center, Mie University, Tsu, Japan.

Department of Medical Informatics, Mie University Hospital, Tsu, Japan.

出版信息

J Med Internet Res. 2023 Aug 22;25:e45834. doi: 10.2196/45834.

DOI:10.2196/45834
PMID:37606971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10481224/
Abstract

BACKGROUND

Shift workers are at high risk of developing sleep disorders such as shift worker sleep disorder or chronic insomnia. Cognitive behavioral therapy (CBT) is the first-line treatment for insomnia, and emerging evidence shows that internet-based CBT is highly effective with additional features such as continuous tracking and personalization. However, there are limited studies on internet-based CBT for shift workers with sleep disorders.

OBJECTIVE

This study aimed to evaluate the impact of a 4-week, physician-assisted, internet-delivered CBT program incorporating machine learning-based well-being prediction on the sleep duration of shift workers at high risk of sleep disorders. We evaluated these outcomes using an internet-delivered CBT app and fitness trackers in the intensive care unit.

METHODS

A convenience sample of 61 shift workers (mean age 32.9, SD 8.3 years) from the intensive care unit or emergency department participated in the study. Eligible participants were on a 3-shift schedule and had a Pittsburgh Sleep Quality Index score ≥5. The study comprised a 1-week baseline period, followed by a 4-week intervention period. Before the study, the participants completed questionnaires regarding the subjective evaluation of sleep, burnout syndrome, and mental health. Participants were asked to wear a commercial fitness tracker to track their daily activities, heart rate, and sleep for 5 weeks. The internet-delivered CBT program included well-being prediction, activity and sleep chart, and sleep advice. A job-based multitask and multilabel convolutional neural network-based model was used for well-being prediction. Participant-specific sleep advice was provided by sleep physicians based on daily surveys and fitness tracker data. The primary end point of this study was sleep duration. For continuous measurements (sleep duration, steps, etc), the mean baseline and week-4 intervention data were compared. The 2-tailed paired t test or Wilcoxon signed rank test was performed depending on the distribution of the data.

RESULTS

In the fourth week of intervention, the mean daily sleep duration for 7 days (6.06, SD 1.30 hours) showed a statistically significant increase compared with the baseline (5.54, SD 1.36 hours; P=.02). Subjective sleep quality, as measured by the Pittsburgh Sleep Quality Index, also showed statistically significant improvement from baseline (9.10) to after the intervention (7.84; P=.001). However, no significant improvement was found in the subjective well-being scores (all P>.05). Feature importance analysis for all 45 variables in the prediction model showed that sleep duration had the highest importance.

CONCLUSIONS

The physician-assisted internet-delivered CBT program targeting shift workers with a high risk of sleep disorders showed a statistically significant increase in sleep duration as measured by wearable sensors along with subjective sleep quality. This study shows that sleep improvement programs using an app and wearable sensors are feasible and may play an important role in preventing shift work-related sleep disorders.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/24799.

摘要

背景

轮班工人患睡眠障碍的风险很高,例如轮班工作睡眠障碍或慢性失眠。认知行为疗法(CBT)是失眠的一线治疗方法,新出现的证据表明,基于互联网的 CBT 非常有效,并且具有连续跟踪和个性化等附加功能。然而,针对睡眠障碍轮班工人的基于互联网的 CBT 研究有限。

目的

本研究旨在评估为期 4 周、由医生协助的、基于互联网的 CBT 计划对睡眠障碍高危轮班工人的睡眠持续时间的影响。我们使用互联网提供的 CBT 应用程序和健身追踪器在重症监护病房评估了这些结果。

方法

本研究便利地选取了来自重症监护病房或急诊室的 61 名轮班工人(平均年龄 32.9 岁,标准差 8.3 岁)参加了这项研究。合格的参与者需要上三班倒班,并且匹兹堡睡眠质量指数评分≥5。研究包括 1 周的基线期,随后是 4 周的干预期。在研究之前,参与者完成了关于睡眠主观评估、倦怠综合征和心理健康的问卷。参与者被要求佩戴商业健身追踪器,以在 5 周内跟踪他们的日常活动、心率和睡眠。互联网提供的 CBT 计划包括幸福感预测、活动和睡眠图表以及睡眠建议。使用基于多任务和多标签卷积神经网络的模型进行幸福感预测。基于日常调查和健身追踪器数据,为睡眠医师提供针对特定参与者的睡眠建议。本研究的主要终点是睡眠持续时间。对于连续测量(睡眠持续时间、步数等),比较基线和第 4 周干预的数据。根据数据分布,采用双侧配对 t 检验或 Wilcoxon 符号秩检验。

结果

在干预的第四周,与基线相比(6.06,SD 1.30 小时),7 天的平均每日睡眠时间(5.54,SD 1.36 小时;P=.02)显示出统计学上的显著增加。匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index)衡量的主观睡眠质量也显示出从基线到干预后的统计学显著改善(9.10 分至 7.84 分;P=.001)。然而,主观幸福感评分没有显著改善(均 P>.05)。预测模型中所有 45 个变量的特征重要性分析表明,睡眠持续时间的重要性最高。

结论

针对睡眠障碍高危轮班工人的医生协助的基于互联网的 CBT 计划显示,可穿戴传感器测量的睡眠持续时间以及主观睡眠质量均有统计学显著增加。本研究表明,使用应用程序和可穿戴传感器的睡眠改善计划是可行的,并且可能在预防轮班工作相关睡眠障碍方面发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/69506622523e/jmir_v25i1e45834_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/0bf46ca50785/jmir_v25i1e45834_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/cff3fc90d35d/jmir_v25i1e45834_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/5fd6abc216f9/jmir_v25i1e45834_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/69506622523e/jmir_v25i1e45834_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/0bf46ca50785/jmir_v25i1e45834_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/cff3fc90d35d/jmir_v25i1e45834_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/5fd6abc216f9/jmir_v25i1e45834_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/210b/10481224/69506622523e/jmir_v25i1e45834_fig4.jpg

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