Carnero-Alcázar Manuel, Beltrao-Sial Rosa, Montero-Cruces Lourdes, López-Vyzcaino Miguel, Pérez-Camargo Daniel, Sánchez Rubén, Cobiella-Carnicer Javier, Fernández-Velasco David, Maroto-Castellanos Luis C
Department of Cardiac Surgery, Hospital Clínico San Carlos, Madrid, Spain.
Department of Anesthesiology, Hospital Clínico San Carlos, Madrid, Spain.
Interdiscip Cardiovasc Thorac Surg. 2023 Aug 3;37(2). doi: 10.1093/icvts/ivad143.
We aimed at comparing the risk of major adverse events and length of stay between patients undergoing ultrafast track and conventional fast track.
Retrospective cohort study adjusted by propensity score matching, including patients operated on between March 2020 and December 2022 of any of the following: coronary, valve surgery or ascending aorta surgery. Patients were divided into 2 groups: ultrafast track: extubation in the operating room and fast track: extubation attempted in the first 6 postoperative hours. The primary objective was to compare the risk of the combined event death, lung respiratory outcomes (reintubation, mechanical ventilation longer than 24 h or pneumonia), or acute renal failure.
A total of 1126 patients were included. A total of 579 (51.4%) were extubated in the operating room. A total of 331 pairs were available after matching by propensity score. The risk of the primary outcome was 11.8% (n = 39) in the fast-track group and 6.3% (n = 21) in the ultrafast-track group (P = 0.013), mostly driven by lung adverse events (6.9% vs 2.4%, P = 0.011) while no significant differences were detected in the risk of death (2.4% vs 1.8%, P = 0.77) or acute renal failure (8% vs 6.3%, P = 0.56). The risk of myocardial infarction was higher in the fast-track group (2.7% vs 0%, P = 0.039). The median length of stay in the postoperative intensive care unit was longer in the fast-track group [24.7 h (interquartile range 21.5; 62.9) vs 23.5 h (interquartile range 22; 46), P = 0.015].
In patients undergoing cardiac surgery, extubation in the operating room is associated to a lower risk of postoperative complications (mostly driven by lung adverse events) and length of stay in intensive care unit as compared to fast track.
我们旨在比较接受超快通道和传统快速通道治疗的患者发生主要不良事件的风险及住院时间。
采用倾向得分匹配法进行回顾性队列研究,纳入2020年3月至2022年12月期间接受以下任何一种手术的患者:冠状动脉手术、瓣膜手术或升主动脉手术。患者分为两组:超快通道组:在手术室拔管;快速通道组:术后6小时内尝试拔管。主要目的是比较联合事件(死亡、肺部呼吸结局(再次插管、机械通气超过24小时或肺炎)或急性肾衰竭)的风险。
共纳入1126例患者。其中579例(51.4%)在手术室拔管。倾向得分匹配后共获得331对。快速通道组主要结局的风险为11.8%(n = 39),超快通道组为6.3%(n = 21)(P = 0.013),主要由肺部不良事件驱动(6.9%对2.4%,P = 0.011),而死亡风险(2.4%对1.8%,P = 0.77)或急性肾衰竭风险(8%对6.3%,P = 0.56)无显著差异。快速通道组心肌梗死风险更高(2.7%对0%,P = 0.039)。快速通道组术后重症监护病房的中位住院时间更长[24.7小时(四分位间距21.5;62.9)对23.5小时(四分位间距22;46),P = 0.015]。
在接受心脏手术的患者中,与快速通道相比,在手术室拔管与术后并发症风险较低(主要由肺部不良事件驱动)及重症监护病房住院时间较短相关。