Biomedical Research Center, Qatar University, Doha, Qatar.
Department of Biomedical Science, College of Health Sciences, QU Health, Qatar University, 2713, Doha, Qatar.
Virol J. 2023 Aug 22;20(1):188. doi: 10.1186/s12985-023-02157-1.
Limited data exists on herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections in migrant populations. This study investigated HSV-1 and HSV-2 seroprevalences and associations among craft and manual workers (CMWs) in Qatar who constitute 60% of Qatar's population.
A national population-based cross-sectional seroprevalence survey was conducted on the CMW population, all men, between July 26 and September 9, 2020. 2,612 sera were tested for anti-HSV-1 IgG antibodies using HerpeSelect 1 ELISA IgG kits and for anti-HSV-2 IgG antibodies using HerpeSelect 2 ELISA IgG kits (Focus Diagnostics, USA). Univariable and multivariable logistic regression analyses were conducted to identify associations with HSV-1 and HSV-2 infections.
Serological testing identified 2,171 sera as positive, 403 as negative, and 38 as equivocal for HSV-1 antibodies, and 300 sera as positive, 2,250 as negative, and 62 as equivocal for HSV-2 antibodies. HSV-1 and HSV-2 seroprevalences among CMWs were estimated at 84.2% (95% CI 82.8-85.6%) and 11.4% (95% CI 10.1-12.6%), respectively. HSV-1 infection was associated with nationality, educational attainment, and occupation. HSV-2 infection was associated with age, nationality, and educational attainment.
Over 80% of CMWs are infected with HSV-1 and over 10% are infected with HSV-2. The findings highlight the need for sexual health programs to tackle sexually transmitted infections among the CMW population.
关于移民人群中单纯疱疹病毒 1 型（HSV-1）和 2 型（HSV-2）感染的数据有限。本研究调查了卡塔尔手工艺和体力劳动者（CMWs）中的 HSV-1 和 HSV-2 血清流行率以及两者之间的关联，这些人占卡塔尔人口的 60%。
2020 年 7 月 26 日至 9 月 9 日，对全国范围内的 CMW 人群（均为男性）进行了一项基于人群的横断面血清流行率调查。使用 HerpeSelect 1 ELISA IgG 试剂盒检测 2612 份血清中的抗 HSV-1 IgG 抗体，使用 HerpeSelect 2 ELISA IgG 试剂盒（美国焦点诊断公司）检测抗 HSV-2 IgG 抗体。采用单变量和多变量逻辑回归分析来确定与 HSV-1 和 HSV-2 感染相关的因素。
血清学检测发现 2171 份血清的 HSV-1 抗体为阳性，403 份为阴性，38 份为可疑；300 份血清的 HSV-2 抗体为阳性，2250 份为阴性，62 份为可疑。CMWs 的 HSV-1 和 HSV-2 血清流行率估计分别为 84.2%（95%CI 82.8-85.6%）和 11.4%（95%CI 10.1-12.6%）。HSV-1 感染与国籍、受教育程度和职业有关。HSV-2 感染与年龄、国籍和受教育程度有关。
超过 80%的 CMW 感染了 HSV-1，超过 10%的人感染了 HSV-2。这些发现强调了需要开展性健康项目，以解决 CMW 人群中的性传播感染问题。
