Palkovits M, Elekes I, Láng T, Patthy A
J Neurochem. 1986 Nov;47(5):1333-5. doi: 10.1111/j.1471-4159.1986.tb00761.x.
Concentrations of taurine have been measured in 44 microdissected rat brain nuclei or areas. Taurine is ubiquitously present and distributed unevenly in the rat brain: the ratio of the highest (pyriform cortex) to lowest (midbrain reticular formation) concentrations is 4.7:1. High taurine levels were found in cerebral cortical areas, caudate-putamen, cerebellum, median eminence, and supraoptic nucleus. Acute pain stress reduced taurine levels in the hypothalamus and the lower brainstem nuclei but not in cortical areas. Increased locomotor and behavioral activities following a high dose of amphetamine elevated taurine concentrations significantly in the substantia nigra and locus ceruleus.
已对44个经显微切割的大鼠脑细胞核或脑区中的牛磺酸浓度进行了测定。牛磺酸在大鼠脑中普遍存在且分布不均：最高浓度（梨状皮质）与最低浓度（中脑网状结构）之比为4.7:1。在大脑皮质区域、尾状核 - 壳核、小脑、正中隆起和视上核中发现了高牛磺酸水平。急性疼痛应激降低了下丘脑和低位脑干核中的牛磺酸水平，但皮质区域未受影响。高剂量苯丙胺后运动和行为活动增加，显著提高了黑质和蓝斑中的牛磺酸浓度。
