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在瘤内注射活卡介苗或卡介苗细胞壁后,已形成的口腔肿瘤发生消退。

Regression of established oral tumors after intralesional injection of living BCG or BCG cell walls.

作者信息

Zbar B, Canti G, Rapp H J, Bier J, Borsos T

出版信息

Cancer. 1979 Apr;43(4):1304-7. doi: 10.1002/1097-0142(197904)43:4<1304::aid-cncr2820430418>3.0.co;2-l.

DOI:10.1002/1097-0142(197904)43:4<1304::aid-cncr2820430418>3.0.co;2-l
PMID:376088
Abstract

Oral tumors with associated cervical lymph node metastases developed after injection of tumor cells into buccal pads of inbred guinea pigs. Intralesional injection of living BCG or BCG cell walls (CW) caused regression of established tumors, prevented the development of cervical lymph node metastases and led to the development of host resistance to the growth of subsequent tumor transplant.

摘要

将肿瘤细胞注射到近交系豚鼠的颊垫后,出现了伴有颈部淋巴结转移的口腔肿瘤。瘤内注射活卡介苗或卡介苗细胞壁(CW)可使已形成的肿瘤消退,防止颈部淋巴结转移的发生,并导致宿主对随后肿瘤移植生长产生抗性。

相似文献

1
Regression of established oral tumors after intralesional injection of living BCG or BCG cell walls.在瘤内注射活卡介苗或卡介苗细胞壁后,已形成的口腔肿瘤发生消退。
Cancer. 1979 Apr;43(4):1304-7. doi: 10.1002/1097-0142(197904)43:4<1304::aid-cncr2820430418>3.0.co;2-l.
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Safety and efficacy of living BCG or BCG cell walls (CW) in the treatment of guinea pig hepatoma.活卡介苗或卡介苗细胞壁(CW)治疗豚鼠肝癌的安全性和有效性。
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Histologic and ultrastructural studies of tumor regression in inbred guinea pigs after intralesional injection of Mycobacterium bovis (BCG).对近交系豚鼠瘤内注射牛分枝杆菌(卡介苗)后肿瘤消退的组织学和超微结构研究。
Natl Cancer Inst Monogr. 1973 Dec;39:71-85.
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Regression by active specific immunotherapy of established dermal tumor transplants and lymph node metastases in guinea pigs.通过主动特异性免疫疗法对豚鼠已建立的皮肤肿瘤移植和淋巴结转移进行消退。
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