Javadpour N, Bagley D H, Zbar B
J Natl Cancer Inst. 1979 Jun;62(6):1479-81.
Inbred Sewall Wright strain 2 male guinea pigs with established intradermal tumors and microscopic lymph node metastases were treated either by local excision, cryosurgery, or intralesional injection of BCG. Cryosurgery and local excision were effective in eliminating growth of the primary tumor but failed to prevent growth of lymph node metastases. In contrast, intralesional injection of BCG caused regression of primary tumors and prevented growth of lymph node metastases.
具有已形成的皮内肿瘤和微小淋巴结转移的近交系斯瓦尔·赖特2系雄性豚鼠，分别接受局部切除、冷冻手术或瘤内注射卡介苗治疗。冷冻手术和局部切除在消除原发性肿瘤生长方面有效，但未能阻止淋巴结转移的生长。相比之下，瘤内注射卡介苗导致原发性肿瘤消退，并阻止了淋巴结转移的生长。
