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伪装成急性ST段抬高型心肌梗死的应激性心肌病

Stress-Induced Cardiomyopathy Masquerading as Acute ST-Segment Elevation Myocardial Infarction.

作者信息

Nepal Subash, Aiello Dana, Ojha Kamala

机构信息

Internal Medicine, Upstate Medical University, Syracuse, USA.

Cardiovascular Disease, Upstate University Hospital, Syracuse, USA.

出版信息

Cureus. 2023 Jul 20;15(7):e42181. doi: 10.7759/cureus.42181. eCollection 2023 Jul.

Abstract

Myocardial stress can lead to a myriad of cardiovascular complications, and stress-induced cardiomyopathy is the predominant manifestation. Exogenous or endogenous hormonal excess, sepsis, tachycardia, and physical or emotional trauma can lead to neurohormonal and catecholaminergic surges. Stress-induced cardiomyopathy often presents with chest pain, ischemic-like ECG changes, troponin elevation, and wall motion abnormalities in echocardiography. It is a diagnosis of exclusion, and coronary artery disease needs to be ruled out by a normal angiogram as per guidelines. It presents predominantly in postmenopausal women and presentation is similar to acute coronary syndrome (ACS) due to plaque rupture. We report a case of a 72-year-old female who presented to the emergency room with severe anginal chest pain without any preceding stress. ECG showed lateral leads ST-elevation and serial serum troponins were elevated. Emergent cardiac catheterization showed insignificant coronary artery disease. Left ventriculogram and echocardiogram showed a moderately reduced left ventricular systolic function with akinetic-hypokinetic mid to distal myocardial segments and normal basal contraction suggestive of stress-induced cardiomyopathy.

摘要

心肌应激可导致多种心血管并发症,应激性心肌病是其主要表现形式。外源性或内源性激素过量、脓毒症、心动过速以及身体或情绪创伤均可导致神经激素和儿茶酚胺激增。应激性心肌病常表现为胸痛、类似缺血的心电图改变、肌钙蛋白升高以及超声心动图显示的室壁运动异常。这是一种排除性诊断,需根据指南通过正常的血管造影排除冠状动脉疾病。该病主要发生在绝经后女性,其表现与因斑块破裂所致的急性冠状动脉综合征(ACS)相似。我们报告一例72岁女性患者,该患者无任何前驱应激因素,因严重心绞痛性胸痛就诊于急诊室。心电图显示侧壁导联ST段抬高,系列血清肌钙蛋白升高。急诊心脏导管检查显示冠状动脉疾病不明显。左心室造影和超声心动图显示左心室收缩功能中度降低,心肌中至远端节段运动减弱或无运动,基底节段收缩正常,提示为应激性心肌病。

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