Guo Yining, Wu Defu, Jin Yu, Tian Yanjie, Li Xuemin
Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Front Psychiatry. 2023 Aug 8;14:1174404. doi: 10.3389/fpsyt.2023.1174404. eCollection 2023.
To investigate the prevalence and risk factors for depression and anxiety in patients with nasolacrimal duct obstruction (NLDO).
We conducted a telephone-based survey of patients with NLDO who underwent dacryocystorhinostomy (DCR) at the Department of Ophthalmology of Peking University Third Hospital in China between January 2016 and January 2021. Depression and anxiety were assessed with the PHQ-9 (range 0-25) and STAI (range 20-80) scales. PHQ-9 ≥ 5 and STAI ≥ 55 were considered clinically significant. Logistic regression and linear regression were performed to determine the factors related to depression and anxiety.
Of 565 patients approached, 344 (60.9%) completed the survey. A total of 13.1% of patients had mild-severe depression and 63.4% had severe anxiety. Univariate logistic regression revealed that hypertension, dry eye, and cataract were associated with mild to severe depression ( = 0.018, 0.045, 0.035, respectively). Dry eye was associated with severe anxiety ( = 0.007). Univariate linear regression revealed that male and income levels were significantly negatively correlated with PHQ-9 scores ( = 0.011, 0.010, respectively). Hypertension and dry eye were significantly positively correlated with PHQ-9 scores ( = 0.030, < 0.001, respectively). Male, income levels, and educational levels were significantly negatively correlated with STAI scores ( = 0.022, < 0.001, = 0.005, respectively). Dry eye was significantly positively correlated with STAI scores ( < 0.001).
Prevalence of depression and anxiety disorders was relatively high among NLDO patients. Our results demonstrate the importance of depression and anxiety screening and psychosocial support for patients with NLDO, which can improve their quality of life and compliance with medical appointments.
探讨鼻泪管阻塞（NLDO）患者抑郁和焦虑的患病率及危险因素。
我们对2016年1月至2021年1月在中国北京大学第三医院眼科接受泪囊鼻腔吻合术（DCR）的NLDO患者进行了电话调查。采用PHQ-9量表（范围0 - 25）和STAI量表（范围20 - 80）评估抑郁和焦虑情况。PHQ-9≥5且STAI≥55被认为具有临床意义。进行逻辑回归和线性回归以确定与抑郁和焦虑相关的因素。
在565名受访患者中，344名（60.9%）完成了调查。共有13.1%的患者患有轻至重度抑郁，63.4%的患者患有重度焦虑。单因素逻辑回归显示，高血压、干眼和白内障与轻至重度抑郁相关（分别为 = 0.018、0.045、0.035）。干眼与重度焦虑相关（ = 0.007）。单因素线性回归显示，男性和收入水平与PHQ-9评分显著负相关（分别为 = 0.011、0.010）。高血压和干眼与PHQ-9评分显著正相关（分别为 = 0.030、 < 0.001）。男性、收入水平和教育水平与STAI评分显著负相关（分别为 = 0.022、 < 0.001、 = 0.005）。干眼与STAI评分显著正相关（ < 0.001）。
NLDO患者中抑郁和焦虑障碍的患病率相对较高。我们的结果表明，对NLDO患者进行抑郁和焦虑筛查以及心理社会支持非常重要，这可以提高他们的生活质量和就医依从性。
