Zambrano Peralta P, Ortiz Quito M, Guerrero Ortiz F, Cervantes Anaya L
Universidad Católica de Cuenca, Sede Matriz, Cuenca, Ecuador.
Universidad Católica de Cuenca, Sede Matriz, Cuenca, Ecuador.
Arch Soc Esp Oftalmol (Engl Ed). 2023 Oct;98(10):568-576. doi: 10.1016/j.oftale.2023.08.001. Epub 2023 Aug 22.
The purpose of this investigation is to determine the efficacy of orthokeratology (OK) compared to orthokeratology combined with atropine (AOK) for the control of myopia in children. A systematic review that included systematic reviews with meta-analyses, as well as randomized and controlled clinical trials, was carried out in the PubMed, Web of Science, Scopus, Cochrane Library, ProQuest, Taylor & Francis, Science Direct databases, as well as a manual search. Of the Q1-Q4 journals of the Scimago Journal & Country Rank, published in the last 5 years in English and Spanish. Eighteen studies that met the eligibility criteria were considered. The articles selected included 6,866 patients for analysis, where orthokeratology combined with 0.01% atropine was found to be more effective due to its ability to reduce the progression of myopia and axial elongation. In our investigation, it was determined that there could be an additive effect in the combination of 0.01% atropine with orthokeratology in a period of 1-2 years of treatment in patients with mild myopia; however, more multiethnic studies should be carried out, in where a correct evaluation of the progression of myopia, genetic and environmental factors that may influence the results is considered.
本研究的目的是确定角膜塑形术（OK）与角膜塑形术联合阿托品（AOK）相比在控制儿童近视方面的疗效。在PubMed、科学网、Scopus、考克兰图书馆、ProQuest、泰勒与弗朗西斯、科学Direct数据库以及手动检索中进行了一项系统评价，该评价包括带有荟萃分析的系统评价以及随机对照临床试验。检索了过去5年以英文和西班牙文发表在Scimago期刊与国家排名的Q1-Q4期刊。共纳入18项符合纳入标准的研究。所选文章纳入6866例患者进行分析，结果发现角膜塑形术联合0.01%阿托品因能够减少近视进展和眼轴伸长而更有效。在我们的研究中，确定在轻度近视患者1-2年的治疗期内，0.01%阿托品与角膜塑形术联合使用可能存在相加效应；然而，应该开展更多的多民族研究，其中要考虑对近视进展、可能影响结果的遗传和环境因素进行正确评估。
