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近视中遗传与环境的相互作用:综述

Crosstalk between heredity and environment in myopia: An overview.

作者信息

Hao Jiawen, Yang Zhaohui, Zhang Ruixue, Ma Zhongyu, Liu Jinpeng, Bi Hongsheng, Guo Dadong

机构信息

Shandong University of Traditional Chinese Medicine, Jinan, 250002, China.

Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250002, China.

出版信息

Heliyon. 2024 Apr 16;10(8):e29715. doi: 10.1016/j.heliyon.2024.e29715. eCollection 2024 Apr 30.

DOI:10.1016/j.heliyon.2024.e29715
PMID:38660258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11040123/
Abstract

In recent years, the prevalence of myopia has gradually increased, and it has become a significant global public health problem in the 21st century, posing a serious challenge to human eye health. Currently, it is confirmed that the development of myopia is attributed to the combined action of genes and environmental factors. Thus, elucidating the risk factors and pathogenesis of myopia is of great significance for the prevention and control of myopia. To elucidate the impact of gene-environment interaction on myopia, we used the Pubmed database to search for literature related to myopia. Search terms are as follows: myopia, genes, environmental factors, gene-environment interaction, and treatment. This paper reviews the effects of gene and environmental interaction on myopia.

摘要

近年来,近视的患病率逐渐上升,已成为21世纪一个重大的全球公共卫生问题,对人类眼睛健康构成了严峻挑战。目前,已证实近视的发展归因于基因和环境因素的共同作用。因此,阐明近视的危险因素和发病机制对近视的防控具有重要意义。为了阐明基因-环境相互作用对近视的影响,我们使用PubMed数据库搜索与近视相关的文献。检索词如下:近视、基因、环境因素、基因-环境相互作用和治疗。本文综述了基因与环境相互作用对近视的影响。

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New Frontiers in Myopia Progression in Children.儿童近视进展的新前沿
J Clin Med. 2024 Dec 2;13(23):7314. doi: 10.3390/jcm13237314.
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Int J Ophthalmol. 2024 Nov 18;17(11):2082-2092. doi: 10.18240/ijo.2024.11.15. eCollection 2024.

本文引用的文献

1
Efficacy of Soft Contact Lenses for Myopia Control: A Systematic Review.软性接触镜控制近视的疗效:一项系统评价。
Semin Ophthalmol. 2024 Apr;39(3):185-192. doi: 10.1080/08820538.2023.2271063. Epub 2023 Oct 18.
2
Orthokeratology vs. orthokeratology combined with atropine for the control of myopia in children: systematic review.角膜塑形术与角膜塑形术联合阿托品控制儿童近视的疗效比较:系统评价
Arch Soc Esp Oftalmol (Engl Ed). 2023 Oct;98(10):568-576. doi: 10.1016/j.oftale.2023.08.001. Epub 2023 Aug 22.
3
[The relationship between classroom environment and myopia].[教室环境与近视之间的关系]
Zhonghua Liu Xing Bing Xue Za Zhi. 2023 Apr 10;44(4):598-606. doi: 10.3760/cma.j.cn112338-20220824-00729.
4
Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia.教育与 GJD2、RBFOX1、LAMA2、KCNQ5 和 LRRC4C 附近的遗传变异相互作用,导致近视易感性。
PLoS Genet. 2022 Nov 17;18(11):e1010478. doi: 10.1371/journal.pgen.1010478. eCollection 2022 Nov.
5
The Connection between High Myopia Patients and MiR-708a or MiR-148 Expression Levels in Aqueous Studies of Visual Acuity.高度近视患者与房水中 miR-708a 或 miR-148 表达水平与视力的关系研究。
Biomed Res Int. 2022 Oct 13;2022:3363830. doi: 10.1155/2022/3363830. eCollection 2022.
6
Decreased Levels of DNA Methylation in the PCDHA Gene Cluster as a Risk Factor for Early-Onset High Myopia in Young Children.PCDHA 基因簇中 DNA 甲基化水平降低可作为儿童早发性高度近视的危险因素。
Invest Ophthalmol Vis Sci. 2022 Aug 2;63(9):31. doi: 10.1167/iovs.63.9.31.
7
Electroacupuncture Improves Choroidal Blood Flow to Inhibit the Development of Lens-Induced Myopia in Guinea Pigs.电针改善豚鼠脉络膜血流以抑制晶状体诱导性近视的发展。
Evid Based Complement Alternat Med. 2022 Jun 24;2022:3286583. doi: 10.1155/2022/3286583. eCollection 2022.
8
Genetic susceptibility to high myopia in Han Chinese population.汉族人群高度近视的遗传易感性。
Open Life Sci. 2022 May 17;17(1):512-516. doi: 10.1515/biol-2022-0055. eCollection 2022.
9
Hsa-miR-142-3p reduces collagen I in human scleral fibroblasts by targeting TGF-β1 in high myopia.Hsa-miR-142-3p 通过靶向 TGF-β1 减少高度近视患者巩膜成纤维细胞中胶原 I 的表达。
Exp Eye Res. 2022 Jun;219:109023. doi: 10.1016/j.exer.2022.109023. Epub 2022 Mar 8.
10
Proposed as a High Myopia Susceptibility Gene in Chinese Population.在中国人群中被提议作为高度近视易感基因。
Front Genet. 2022 Jan 12;12:775797. doi: 10.3389/fgene.2021.775797. eCollection 2021.