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通过一种易于互换的可控释放Accurel微型装置来调控大鼠脑脊液中血管加压素的水平。

Manipulation of vasopressin level in the cerebrospinal fluid of the rat by means of an easily interchangeable controlled-delivery Accurel mini-device.

作者信息

Kruisbrink J, Van der Woude T P, Boer G J, Mirmiran M

出版信息

J Neurosci Methods. 1986 Aug;17(2-3):103-8. doi: 10.1016/0165-0270(86)90063-4.

DOI:10.1016/0165-0270(86)90063-4
PMID:3762220
Abstract

The procedure described for the continuous release of vasopressin (VP) in the rat lateral ventricle via implantation of a VP-loaded Accurel/collodion mini-device has now been further developed, allowing the introduction, removal and exchange of the Accurel device through a polyethylene guide cannula. In this way, manipulation of the VP level in the cerebrospinal fluid can easily be accomplished. VP levels were measured by radioimmunoassay in liquor withdrawn from the cisterna magna.

摘要

通过植入负载血管加压素（VP）的Accurel/火棉胶微型装置在大鼠侧脑室中持续释放VP的程序现已进一步改进，允许通过聚乙烯引导套管引入、取出和更换Accurel装置。通过这种方式，可以轻松实现脑脊液中VP水平的调控。通过放射免疫分析法测定从枕大池抽取的脑脊液中的VP水平。

相似文献

1
Manipulation of vasopressin level in the cerebrospinal fluid of the rat by means of an easily interchangeable controlled-delivery Accurel mini-device.通过一种易于互换的可控释放Accurel微型装置来调控大鼠脑脊液中血管加压素的水平。
J Neurosci Methods. 1986 Aug;17(2-3):103-8. doi: 10.1016/0165-0270(86)90063-4.
2
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