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Spatiotemporal Transcriptome Analysis Reveals Activation of the AP1 Pathway in the Ovarian Microenvironment during the Transition from Premenopause to Postmenopause.

作者信息

Pei Wendi, Cao Xiaomin, Zhang Puyao, Fu Lin, Zhou Ping, Liu Ye, Fan Yong, Xu Fengqin, Cao Canhui, Yu Yang

机构信息

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction, Ministry of Education, Peking University Third Hospital, Beijing, China.

Reproductive Medicine Center, Tianjin First Central Hospital, Tianjin, China.

出版信息

Aging Dis. 2024 Apr 1;15(2):445-448. doi: 10.14336/AD.2023.0707-1.

DOI:10.14336/AD.2023.0707-1
PMID:37624093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10917534/
Abstract
摘要

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本文引用的文献

1
Single-cell transcriptome analysis of the mouse and primate ovaries reveals oocyte-specific expression patterns of risk genes in ovarian aging.小鼠和灵长类动物卵巢的单细胞转录组分析揭示了卵巢衰老中风险基因的卵母细胞特异性表达模式。
MedComm (2020). 2023 Feb 16;4(2):e209. doi: 10.1002/mco2.209. eCollection 2023 Apr.
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Single-cell profiling of mouse and primate ovaries identifies high levels of for stromal cells in ovarian aging.小鼠和灵长类卵巢的单细胞分析确定了卵巢衰老过程中基质细胞的高水平情况。
Mol Ther Nucleic Acids. 2022 Nov 25;31:1-12. doi: 10.1016/j.omtn.2022.11.020. eCollection 2023 Mar 14.
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Cell2location maps fine-grained cell types in spatial transcriptomics.
细胞定位图谱精细的细胞类型在空间转录组学。
Nat Biotechnol. 2022 May;40(5):661-671. doi: 10.1038/s41587-021-01139-4. Epub 2022 Jan 13.
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Genetic insights into biological mechanisms governing human ovarian ageing.遗传视角下人类卵巢衰老的生物学机制。
Nature. 2021 Aug;596(7872):393-397. doi: 10.1038/s41586-021-03779-7. Epub 2021 Aug 4.
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The FOS/AP-1 Regulates Metabolic Changes and Cholesterol Synthesis in Human Periovulatory Granulosa Cells.FOS/AP-1 调控人排卵前颗粒细胞的代谢变化和胆固醇合成。
Endocrinology. 2021 Sep 1;162(9). doi: 10.1210/endocr/bqab127.
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The ovarian stroma as a new frontier.卵巢间质：新前沿
Reproduction. 2020 Sep;160(3):R25-R39. doi: 10.1530/REP-19-0501.
7
Spatiotemporal changes in mechanical matrisome components of the human ovary from prepuberty to menopause.人类卵巢从青春期前到绝经期机械基质组件的时空变化。
Hum Reprod. 2020 Jun 1;35(6):1391-1410. doi: 10.1093/humrep/deaa100.
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Single-Cell Transcriptomic Atlas of Primate Ovarian Aging.灵长类动物卵巢衰老的单细胞转录组图谱
Cell. 2020 Feb 6;180(3):585-600.e19. doi: 10.1016/j.cell.2020.01.009. Epub 2020 Jan 30.
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Perturbation-response genes reveal signaling footprints in cancer gene expression.扰动响应基因揭示癌症基因表达中的信号印记。
Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6.
10
Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention.生物活性天然产物靶向激活蛋白 1 信号通路：癌症预防和干预的可能治疗策略。
Pharmacol Res. 2018 Feb;128:366-375. doi: 10.1016/j.phrs.2017.09.014. Epub 2017 Sep 23.