Long Christopher Patrick, Ameri Hossein
Department of Ophthalmology, USC Roski Eye Institute, Keck School of Medicine, University of Southern California, 1450 San Pablo St #4400, Los Angeles, CA 90033, USA.
J Clin Med. 2023 Aug 14;12(16):5286. doi: 10.3390/jcm12165286.
(1) Background: mfERG testing is used to study the function of cone photoreceptors in the central retina. Various filters including "smoothing" (Smooth) and "adaptive data filtering" (Adapt) are used to simplify raw data. This study will seek to characterize the effect of data modification on raw patient data. (2) Methods: This was a retrospective study of patients with mfERG results at our institution. For each patient, raw mfERG data without filtering, with smooth level 4 modifier applied, and with adapt level 4 applied were collected and compared. (4) Conclusions: In all patients, smoothing and adaptive filter modifiers create statistically significant differences in both P1 latency and P1 amplitude values when compared to raw data. The impacts of these filters demonstrated in this study should impact physicians' decision making when interpreting mfERG results.
（1）背景：多焦视网膜电图（mfERG）测试用于研究视网膜中央区视锥光感受器的功能。包括“平滑”（Smooth）和“自适应数据滤波”（Adapt）在内的各种滤波器用于简化原始数据。本研究旨在描述数据修改对患者原始数据的影响。（2）方法：这是一项对我院有mfERG结果患者的回顾性研究。对于每位患者，收集并比较未滤波、应用平滑等级4修正器以及应用自适应等级4修正器的原始mfERG数据。（4）结论：在所有患者中，与原始数据相比，平滑和自适应滤波修正器在P1潜伏期和P1振幅值方面均产生了具有统计学意义的差异。本研究中所展示的这些滤波器的影响，在解读mfERG结果时应会影响医生的决策。
