Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Research Center for Environmental Determinants of Health, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Sci Rep. 2022 Mar 8;12(1):4057. doi: 10.1038/s41598-022-07896-9.
In this cross-sectional population-based study, we used the baseline data of the Prospective Epidemiologic Research Studies in IrAN cohort study collected in Iran from 2014 to 2020. The main outcomes were the prevalence of hypertension and proportion of awareness, treatment, and control based on the 2017 ACC/AHA guideline compared to the seventh report of the Joint National Committee (JNC7). Of the total of 163,770 participants, aged 35-70 years, 55.2% were female. The sex-age standardized prevalence of hypertension was 22.3% (95% CI 20.6, 24.1) based on the JNC7 guideline and 36.5% (31.1, 41.8) based on the ACC/AHA guideline. A total of 24,312 participants [14.1% (10.1, 18.1)] were newly diagnosed based on the ACC/AHA guideline. Compared to adults diagnosed with hypertension based on the JNC7 guideline, the newly diagnosed participants were mainly young literate males who had low levels of risk factors and were free from conventional comorbidities of hypertension. About 30.7% (25.9, 35.4) of them (4.3% of the entire population) were eligible for pharmacologic intervention based on the ACC/AHA guideline. Implementation of the new guideline may impose additional burden on health systems. However, early detection and management of elevated blood pressure may reduce the ultimate burden of hypertension in Iran.
在这项横断面基于人群的研究中，我们使用了 2014 年至 2020 年在伊朗进行的 Prospective Epidemiologic Research Studies in IrAN 队列研究的基线数据。主要结局是根据 2017 年 ACC/AHA 指南与第七版联合国家委员会（JNC7）相比，高血压的患病率和知晓率、治疗率和控制率。在总共 163770 名年龄在 35-70 岁的参与者中，55.2%为女性。根据 JNC7 指南，高血压的性别年龄标准化患病率为 22.3%（95%CI20.6，24.1），根据 ACC/AHA 指南为 36.5%（31.1，41.8）。共有 24312 名参与者[14.1%（10.1，18.1）]根据 ACC/AHA 指南被新诊断为高血压。与根据 JNC7 指南诊断为高血压的成年人相比，新诊断的参与者主要是年轻、有文化的男性，他们的危险因素水平较低，没有高血压的传统合并症。根据 ACC/AHA 指南，约 30.7%（25.9，35.4）的人（占总人口的 4.3%）有资格进行药物干预。实施新指南可能会给卫生系统带来额外的负担。然而，早期发现和管理血压升高可能会减轻伊朗高血压的最终负担。
