Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia.
Health Center "Novi Sad", 21000 Novi Sad, Serbia.
Medicina (Kaunas). 2023 Jul 29;59(8):1396. doi: 10.3390/medicina59081396.
Knee osteoarthritis (KOA) is a widespread chronic joint disease characterized by functional limitations and pain. Functioning restrictions exert a detrimental impact on societal integration, relationships, and psychological well-being, resulting in significant emotional distress in KOA patients. The objective of this study is to examine how various risk factors impact the emotional well-being of individuals with KOA. This prospective cross-sectional study involved 154 postmenopausal women treated at the Special Hospital for Rheumatic Diseases in Novi Sad, Serbia. The experimental group comprised 97 individuals with chronic knee pain and structural knee damage (Kellgren-Lawrence (KL) scale II-IV), while the control group had 53 individuals with chronic knee pain but no structural knee damage (KL scale 0-I). The collected data consisted of sociodemographic factors, general characteristics, associated diseases, and laboratory results. Adequate anthropometric measurements were conducted, and all subjects were required to complete the SF-36 RAND questionnaire. The analysis identified several variables that independently influenced emotional well-being. These included pain intensity (beta (β) 0.21; 95% CI: 0.03-0.20; < 0.01), social functioning (beta (β) 0.47; 95% CI: 0.23-0.43; < 0.001), physical functioning (beta (β) 0.23; 95% CI: 0.04-0.21; < 0.01), and education level (8-12 years: beta (β) 0.25; 95% CI: 1.47-9.41; < 0.01; >12 years: beta (β) 0.27; 95% CI: 2.51-12.67; < 0.01). However, the multivariate model revealed that only social functioning (beta (β) 0.57; 95% CI: 0.27-0.53; < 0.001) and education level (8-12 years: beta (β) 0.21; 95% CI: 1.10-8.260; < 0.05; >12 years: beta (β) 0.21; 95% CI: 1.18-10.30; < 0.05) were significantly associated with emotional well-being in KOA patients. The findings of this study indicate that a reduced social functioning and a lower educational attainment are linked to a poorer emotional well-being among patients with KOA.
膝关节骨关节炎（KOA）是一种广泛存在的慢性关节疾病，其特征为功能受限和疼痛。功能受限对社会融合、人际关系和心理健康产生不利影响，导致 KOA 患者出现明显的情绪困扰。本研究旨在探讨各种风险因素如何影响 KOA 患者的情绪健康。
这项前瞻性的横断面研究涉及了 154 名在塞尔维亚诺维萨德风湿疾病专科医院接受治疗的绝经后女性。实验组包括 97 名患有慢性膝关节疼痛和结构性膝关节损伤（Kellgren-Lawrence（KL）分级 II-IV）的患者，对照组则有 53 名患有慢性膝关节疼痛但无结构性膝关节损伤（KL 分级 0-I）的患者。研究收集了社会人口统计学因素、一般特征、相关疾病和实验室结果等数据。进行了充分的人体测量，并要求所有受试者完成 SF-36 RAND 问卷。
分析确定了一些独立影响情绪健康的变量。这些变量包括疼痛强度（β 0.21；95%CI：0.03-0.20；<0.01）、社会功能（β 0.47；95%CI：0.23-0.43；<0.001）、身体功能（β 0.23；95%CI：0.04-0.21；<0.01）和教育水平（8-12 年：β 0.25；95%CI：1.47-9.41；<0.01；>12 年：β 0.27；95%CI：2.51-12.67；<0.01）。然而，多元模型显示，只有社会功能（β 0.57；95%CI：0.27-0.53；<0.001）和教育水平（8-12 年：β 0.21；95%CI：1.10-8.260；<0.05；>12 年：β 0.21；95%CI：1.18-10.30；<0.05）与 KOA 患者的情绪健康显著相关。
本研究结果表明，社会功能降低和教育程度较低与 KOA 患者情绪健康状况较差有关。
