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合并双胎妊娠的侵袭性盆腔血管黏液瘤:基于文献的诊断、治疗和临床并发症。

Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature.

机构信息

Department of Gynecology and Obstetrics, "Maggiore della Carità" Hospital, University of Piemonte Orientale, 28100 Novara, Italy.

Department of Translational Medicine, University of Piemonte Orientale, 28100 Novara, Italy.

出版信息

Medicina (Kaunas). 2023 Aug 3;59(8):1417. doi: 10.3390/medicina59081417.

DOI:10.3390/medicina59081417
PMID:37629707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10456254/
Abstract

(1) Background: Aggressive angiomyxoma is a mesenchymal cancer that is rare during pregnancy. It is a neoplasm that relapses and infiltrates the nearest structures. Our aim is to evaluate the management and outcomes of an observed case, in light of the current literature. (2) Methods: We observed this condition at the "Maggiore della Carità" Hospital in Novara (Italy) in a patient with an initial twin pregnancy and a suspected pelvic mass. The words "angiomyxoma" and "pregnancy" were searched on the main online scientific search sources (PubMed, Google Scholar, Scopus, WES, and Embase, etc.). (3) Results: The patient underwent surgery with a complicated follow-up, but recent negative controls. We analyzed the literature about the topic and found only 24 similar clinical cases. (4) Conclusions: Considering the current literature, it is useful to assess an aggressive angiomyxoma in the differential diagnosis of soft masses in pregnant women. The treatment of choice is surgical excision, and vaginal delivery is feasible. The therapeutic decision depends on each case.

摘要

(1) 背景:侵袭性血管黏液瘤是一种罕见的妊娠期间发生的间叶性癌症。它是一种易复发并浸润最近结构的肿瘤。我们的目的是根据当前文献评估观察到的病例的处理和结果。

(2) 方法:我们在意大利诺瓦拉的“Maggiore della Carità”医院观察到了这种情况,患者最初怀有双胞胎,且有疑似骨盆肿块。我们在主要的在线科学搜索源(PubMed、Google Scholar、Scopus、WES 和 Embase 等)上搜索了“angiomyxoma”和“pregnancy”这两个词。

(3) 结果:患者接受了手术治疗,但随访过程复杂,最近的检查结果为阴性。我们分析了关于该主题的文献,仅发现了 24 例类似的临床病例。

(4) 结论:考虑到当前的文献,在鉴别诊断妊娠妇女的软组织肿块时,评估侵袭性血管黏液瘤是有用的。首选治疗方法是手术切除,且可行阴道分娩。治疗决策取决于每个病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950f/10456254/4d06453891ec/medicina-59-01417-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950f/10456254/4640bdb1a6e5/medicina-59-01417-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950f/10456254/7d1f2dd3804b/medicina-59-01417-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950f/10456254/4d06453891ec/medicina-59-01417-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950f/10456254/4640bdb1a6e5/medicina-59-01417-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950f/10456254/7d1f2dd3804b/medicina-59-01417-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950f/10456254/4d06453891ec/medicina-59-01417-g003.jpg

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本文引用的文献

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Eradication of Isolated Para-Aortic Nodal Recurrence in a Patient with an Advanced High Grade Serous Ovarian Carcinoma: Our Experience and Review of Literature.晚期高级别浆液性卵巢癌患者孤立性腹主动脉旁淋巴结复发病例的根治:我们的经验和文献复习。
Medicina (Kaunas). 2022 Feb 6;58(2):244. doi: 10.3390/medicina58020244.
2
Genital Prolapse in Pregnant Woman as a Presentation of Aggressive Angiomyxoma: Case Report and Literature Review.孕妇的生殖器脱垂为侵袭性血管黏液瘤的表现:病例报告及文献复习。
Medicina (Kaunas). 2022 Jan 10;58(1):107. doi: 10.3390/medicina58010107.
3
Aggressive angiomyxoma in pregnancy: a case report and literature review.
妊娠性侵袭性血管黏液瘤:病例报告及文献复习。
J Int Med Res. 2020 Jul;48(7):300060520936414. doi: 10.1177/0300060520936414.
4
Treatment Outcomes and Sensitivity to Hormone Therapy of Aggressive Angiomyxoma: A Multicenter, International, Retrospective Study.侵袭性血管黏液瘤的治疗效果和激素治疗敏感性:一项多中心、国际性、回顾性研究。
Oncologist. 2019 Jul;24(7):e536-e541. doi: 10.1634/theoncologist.2018-0338. Epub 2018 Dec 5.
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Aggressive angiomyxoma in pregnancy: A rare and commonly misdiagnosed entity.妊娠期侵袭性血管黏液瘤:一种罕见且常被误诊的疾病。
J Lab Physicians. 2018 Apr-Jun;10(2):245-247. doi: 10.4103/JLP.JLP_179_17.
6
A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?妊娠期间侵袭性血管黏液瘤病例报告:激素起作用吗?
Case Rep Obstet Gynecol. 2016;2016:6810368. doi: 10.1155/2016/6810368. Epub 2016 Nov 15.
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Aggressive Angiomyxoma of Vulva in Pregnancy: A Case Report.妊娠合并外阴侵袭性血管黏液瘤:1例报告
J Obstet Gynaecol India. 2016 Oct;66(Suppl 2):610-612. doi: 10.1007/s13224-016-0870-6. Epub 2016 Mar 31.
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