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妊娠期间侵袭性血管黏液瘤病例报告:激素起作用吗?

A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?

作者信息

Orfanelli Theofano, Kim Chi-Son, Vitez Sally F, Van Gurp James, Misra Neeti

机构信息

Department of Obstetrics, Gynecology and Reproductive Sciences, Rutgers-Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08901, USA.

Department of Pathology, Rutgers-Robert Wood Johnson Medical School, One Robert Wood Johnson Place, MEB 212, New Brunswick, NJ 08903, USA.

出版信息

Case Rep Obstet Gynecol. 2016;2016:6810368. doi: 10.1155/2016/6810368. Epub 2016 Nov 15.

DOI:10.1155/2016/6810368
PMID:27974982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5126394/
Abstract

Aggressive angiomyxoma is a rare, locally invasive tumor that generally affects the perineum and pelvis of reproductive age females. Aggressive angiomyxoma is often misdiagnosed, resulting in the delay of the treatment. Case reports show increased growth of the tumor during pregnancy, thus suggesting a hormonal dependency. We report this rare condition in a 29-year-old primigravid female with a growing mass on the right labium majus at 20 weeks' gestation. The patient also developed a smaller mass on the left labium majus at 37 weeks' gestation. The patient underwent a primary cesarean section with resection of the right labial mass, with a final diagnosis of aggressive angiomyxoma. The lesion on her left labium majus resolved spontaneously postpartum. This case report supports a hormonal involvement in this tumor.

摘要

侵袭性血管黏液瘤是一种罕见的、具有局部侵袭性的肿瘤,通常影响育龄女性的会阴和盆腔。侵袭性血管黏液瘤常被误诊,导致治疗延误。病例报告显示,该肿瘤在孕期生长加快,提示其对激素有依赖性。我们报告了一名29岁初产妇的罕见病例,她在妊娠20周时右侧大阴唇出现肿物并逐渐增大。该患者在妊娠37周时左侧大阴唇也出现了较小的肿物。患者接受了初次剖宫产并切除右侧阴唇肿物,最终诊断为侵袭性血管黏液瘤。其左侧大阴唇的肿物在产后自行消退。本病例报告支持激素与该肿瘤有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d908/5126394/dfe992d4b48d/CRIOG2016-6810368.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d908/5126394/e57f22c31afa/CRIOG2016-6810368.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d908/5126394/dfe992d4b48d/CRIOG2016-6810368.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d908/5126394/e57f22c31afa/CRIOG2016-6810368.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d908/5126394/dfe992d4b48d/CRIOG2016-6810368.002.jpg

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J Int Med Res. 2020 Jul;48(7):300060520936414. doi: 10.1177/0300060520936414.
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