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保加利亚对重组严重急性呼吸综合征冠状病毒2型XAN变体的早期检测:对重组分支这一日益复杂难题的又一部分的初步基因组见解。

Early Detection of the Recombinant SARS-CoV-2 XAN Variant in Bulgaria: Initial Genomic Insights into Yet Another Piece of the Growing Puzzle of Recombinant Clades.

作者信息

Alexiev Ivailo, Ivanov Ivan, Giovanetti Marta, Cella Eleonora, Stoikov Ivan, Donchev Deyan, Grigorova Lyubomira, Gancheva Anna, Dimitrova Reneta, Scarpa Fabio, Korsun Neli, Trifonova Ivelina, Dobrinov Veselin, Kantardjiev Todor, Christova Iva, Ciccozzi Massimo

机构信息

National Center of Infectious and Parasitic Diseases, 1504 Sofia, Bulgaria.

Instituto Rene Rachou Fundação Oswaldo Cruz, Belo Horizonte 30190-009, Minas Gerais, Brazil.

出版信息

Microorganisms. 2023 Aug 9;11(8):2041. doi: 10.3390/microorganisms11082041.

Abstract

The first recombinant SARS-CoV-2 variants were identified in 2022, causing public health concerns. The importance of recombinant variants has increased especially since the WHO designated the recombinant variant XBB and its lineages as subvariants that require monitoring on 20 November 2022. In this study, we provide the first insights into the new SARS-CoV-2 variant named XAN, a recombinant composed of Omicron sub-lineages BA.2 and BA.5. To our knowledge, this is the first report on the recombinant SARS-CoV-2 XAN variant identified in Bulgaria.

摘要

2022年首次发现了重组严重急性呼吸综合征冠状病毒2(SARS-CoV-2)变体,引发了公众对公共卫生的担忧。自世界卫生组织于2022年11月20日将重组变体XBB及其谱系指定为需要监测的亚变体以来,重组变体的重要性尤其增加。在本研究中,我们首次深入了解了名为XAN的新型SARS-CoV-2变体,这是一种由奥密克戎亚谱系BA.2和BA.5组成的重组体。据我们所知,这是在保加利亚发现的重组SARS-CoV-2 XAN变体的首次报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2be5/10457977/a8bd4294ed73/microorganisms-11-02041-g001.jpg

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