儿科眼部药物的安全性如何？

How safe are ocular drugs in pediatrics?

作者信息

Palmer E A

出版信息

Ophthalmology. 1986 Aug;93(8):1038-40. doi: 10.1016/s0161-6420(86)33624-8.

Abstract

In comparison with that of adults, the smaller body mass of children raises questions of dosage. In addition, manifestations of ocular drug toxicity are different in some respects. The ocular drugs causing serious adverse ocular or systemic side effects in children include glaucoma medications, corticosteroids, phenylephrine, and the anticholinergic cycloplegics. The reported complications from using these medications in children will be briefly reviewed, and strategies for minimizing the risk of their adverse effects will be suggested, including a discussion of dosages and techniques of administration.

摘要

与成人相比，儿童较小的体重引发了剂量问题。此外，眼部药物毒性的表现在某些方面有所不同。在儿童中可引起严重眼部或全身副作用的眼部药物包括青光眼药物、皮质类固醇、去氧肾上腺素和抗胆碱能睫状肌麻痹剂。将简要回顾报道的儿童使用这些药物的并发症，并提出将其不良反应风险降至最低的策略，包括讨论剂量和给药技术。