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本文引用的文献

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Cannabinoids in the Pathophysiology of Skin Inflammation.大麻素在皮肤炎症发病机制中的作用。
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Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer.大麻二酚:从植物到人体——一种具有多靶点效应的有前景的生物活性分子,对癌症有作用。
Int J Mol Sci. 2019 Nov 25;20(23):5905. doi: 10.3390/ijms20235905.
3
Review of Common Alternative Herbal "Remedies" for Skin Cancer.
Dermatol Surg. 2019 Jan;45(1):58-67. doi: 10.1097/DSS.0000000000001622.
4
Genetics of metastasis: melanoma and other cancers.转移的遗传学:黑色素瘤和其他癌症。
Clin Exp Metastasis. 2018 Aug;35(5-6):379-391. doi: 10.1007/s10585-018-9893-y. Epub 2018 May 2.
5
The role of cannabinoids in dermatology.大麻素在皮肤病学中的作用。
J Am Acad Dermatol. 2017 Jul;77(1):188-190. doi: 10.1016/j.jaad.2017.02.056. Epub 2017 Apr 14.
6
Misinformation is prevalent in psoriasis-related YouTube videos.与银屑病相关的YouTube视频中普遍存在错误信息。
Dermatol Online J. 2016 Nov 15;22(11):13030/qt7qc9z2m5.
7
Squamous Cell Cancers: A Unified Perspective on Biology and Genetics.鳞状细胞癌:生物学与遗传学的统一视角
Cancer Cell. 2016 May 9;29(5):622-637. doi: 10.1016/j.ccell.2016.04.004.
8
Is YouTube useful as a source of information for Sjögren's syndrome?YouTube作为干燥综合征的信息来源是否有用?
Oral Dis. 2016 Apr;22(3):196-201. doi: 10.1111/odi.12404. Epub 2016 Jan 11.
9
Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death.利用大麻素诱导的细胞毒性自噬来驱动黑色素瘤细胞死亡。
J Invest Dermatol. 2015 Jun;135(6):1629-1637. doi: 10.1038/jid.2015.45. Epub 2015 Feb 10.
10
YouTube for information on rheumatoid arthritis--a wakeup call?YouTube 上有关类风湿关节炎的信息——警钟?
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四氢大麻酚与皮肤癌:YouTube 视频分析。

Tetrahydrocannabinol and Skin Cancer: Analysis of YouTube Videos.

机构信息

Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

Department of Medicine, Riverside Community Hospital, Riverside, CA, United States.

出版信息

JMIR Dermatol. 2021 May 4;4(1):e26564. doi: 10.2196/26564.

DOI:10.2196/26564
PMID:37632811
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10501512/
Abstract

BACKGROUND

Cannabis oil is being used topically by patients with skin cancer as a homeopathic remedy, and has been promoted and popularized on social media, including YouTube. Although topical cannabinoids, especially tetrahydrocannabinol (THC), may have antitumor effects, results from a sparse number of clinical trials and peer-reviewed studies detailing safety and efficacy are still under investigation.

OBJECTIVE

We sought to assess the accuracy, quality, and reliability of THC oil and skin cancer information available on YouTube.

METHODS

The 10 most-viewed videos on THC oil and skin cancer were analyzed with the Global Quality Scale (GQS), DISCERN score, and useful/misleading criteria based on presentation of erroneous and scientifically unproven information. The videos were also inspected for source, length, and audience likes/dislikes. Top comments were additionally examined based on whether they were favorable, unfavorable, or neutral regarding the video content.

RESULTS

All analyzed videos (10/10, 100%) received a GQS score of 1, corresponding to poor quality of content, and 9/10 (90%) videos received a DISCERN score of 0, indicating poor reliability of information presented. All 10 videos were also found to be misleading and not useful according to established criteria. Top comments were largely either favorable (13/27, 48%) or neutral (13/27, 48%) toward the content of the videos, compared to unfavorable (1/27, 4%).

CONCLUSIONS

Dermatologists should be aware that the spread of inaccurate information on skin cancer treatment currently exists on popular social media platforms and may lead to detrimental consequences for patients interested in pursuing alternative or homeopathic approaches.

摘要

背景

一些患有皮肤癌的患者正在将大麻油作为顺势疗法进行局部治疗,并在包括 YouTube 在内的社交媒体上进行推广和普及。虽然局部使用大麻素,尤其是四氢大麻酚(THC),可能具有抗肿瘤作用,但来自少数临床试验和同行评议研究的结果详细描述其安全性和疗效仍在调查中。

目的

我们旨在评估 YouTube 上关于大麻油和皮肤癌的信息的准确性、质量和可靠性。

方法

我们对 THC 油和皮肤癌的 10 个最受欢迎的视频进行了分析,使用全球质量量表(GQS)、DISCERN 评分以及基于错误和未经科学证实的信息呈现的有用/误导性标准进行分析。还检查了视频的来源、长度和观众的喜欢/不喜欢。根据视频内容是否有利、不利或中立,还进一步检查了顶级评论。

结果

所有分析的视频(10/10,100%)的 GQS 评分为 1,对应于内容质量差,9/10(90%)的视频的 DISCERN 评分为 0,表明呈现的信息可靠性差。根据既定标准,所有 10 个视频也被发现具有误导性且无用。顶级评论大多对视频内容持有利(13/27,48%)或中立(13/27,48%)态度,而不利(1/27,4%)态度则相对较少。

结论

皮肤科医生应该意识到,关于皮肤癌治疗的不准确信息目前在流行的社交媒体平台上传播,并可能对有兴趣采用替代或顺势疗法的患者产生不利影响。