Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.
Center for Drug Use and HIV/HCV Research, New York, New York, USA.
Clin Infect Dis. 2024 May 15;78(5):1235-1239. doi: 10.1093/cid/ciad503.
Hepatitis C virus (HCV) elimination is an important global public health goal. However, the United States is not on track to meet the World Health Organization's 2030 targets for HCV elimination. Recently, the White House proposed an HCV elimination plan that includes point-of-care (POC) HCV RNA testing, which is currently in use in many countries but is not approved in the United States. POC HCV RNA testing is crucial for implementing community-based testing and for enabling test-and-treat programs, assessing cure, and monitoring for reinfection. Here, we review the status of POC HCV RNA testing in the United States, discuss factors that are needed for successful implementation, and issue specific public health and policy recommendations that would allow for the use of POC HCV RNA testing to support HCV elimination.
丙型肝炎病毒（HCV）消除是一个重要的全球公共卫生目标。然而，美国并未走上实现世界卫生组织 2030 年 HCV 消除目标的轨道。最近，白宫提出了一项 HCV 消除计划，其中包括即时护理（POC）HCV RNA 检测，该检测目前在许多国家使用，但尚未在美国获得批准。POC HCV RNA 检测对于实施基于社区的检测以及实现检测和治疗方案、评估治愈和监测再感染至关重要。在这里，我们回顾了美国 POC HCV RNA 检测的现状，讨论了成功实施所需的因素，并提出了具体的公共卫生和政策建议，允许使用 POC HCV RNA 检测来支持 HCV 消除。
