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[男性糖尿病患者血清中的丙二醛、α-生育酚和视黄醇含量]

[Malondialdehyde, alpha-tocopherol and retinol content of the blood serum in male diabetics].

作者信息

Gribauskas P S, Norkus A V, Cherniauskene R Ch, Varshkiavichene Z Z, Masal'skene V V

出版信息

Probl Endokrinol (Mosk). 1986 Jul-Aug;32(4):46-9.

PMID:3763573
Abstract

The average concentration of malondialdehyde (MDA) in diabetes mellitus males was not higher than in the age-matched controls whereas alpha-tocopherol levels in diabetes mellitus significantly exceeded the normal disregarding the pattern of the disease and closely correlated with the concentration of triglycerides. Lower concentration of retinol in comparison with the control group was observed in the patients. Relative levels of alpha-tocopherol/MDA and retinol/MDA were age-dependent: in patients under 30 and above 50 the levels of alpha-tocopherol/MDA were significantly higher than in their normal age-matches while in 31-50-old ones no elevation in the above mentioned levels was observed. Retinol/MDA levels were significantly lower in the latter age group. The data are indicative of decreased levels of alpha-tocopherol and retinol in diabetes mellitus patients aged 31-50.

摘要

糖尿病男性患者中丙二醛(MDA)的平均浓度并不高于年龄匹配的对照组,而糖尿病患者体内的α-生育酚水平显著高于正常水平,且与疾病类型无关,与甘油三酯浓度密切相关。与对照组相比,患者体内视黄醇浓度较低。α-生育酚/MDA和视黄醇/MDA的相对水平与年龄有关:30岁以下和50岁以上患者的α-生育酚/MDA水平显著高于其年龄匹配的正常人,而31-50岁患者上述水平未见升高。后一年龄组的视黄醇/MDA水平显著较低。这些数据表明31-50岁糖尿病患者体内α-生育酚和视黄醇水平降低。

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