Gupta Priti, Cunningham Solveig A, Ali Mohammed K, Mohan Sailesh, Mahapatra Pranab, Pati Sanghamitra C
Research Department, Centre for Chronic Disease Control, New Delhi, India.
Department of Global Health, Emory University, Atlanta, Georgia.
Indian J Psychiatry. 2023 Jul;65(7):736-741. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_463_22. Epub 2023 Jul 12.
There is a dearth of data on common multimorbidity clusters and the healthcare costs for individuals with mental health disorders. This study aimed to identify clinically meaningful physical-mental multimorbidity clusters, frequently occurring clusters of conditions, and healthcare utilization patterns and expenditure among patients attending a psychiatric outpatient clinic.
Data were collected in the psychiatric outpatient department among patients aged 18 years and above in February-July 2019 ( = 500); follow-up data on non-communicable disease incidence were collected after 18 months. For analysis, morbidity clusters were defined using two approaches: 1) agglomerative hierarchical clustering method to identify clusters of diseases; and 2) non-hierarchical cluster k mean analysis to identify clusters of patients. Self-reported healthcare costs in these clusters were also calculated.
Two disease clusters were identified: using the 1 approach were; 1) hypertension, diabetes, and mood disorder; 2) Neurotic, stress-related, and somatoform disorders, and acid peptic disease. Three clusters of patients identified using the 2 approach were identified: 1) those with mood disorders and cardiometabolic, musculoskeletal, and thyroid diseases; 2) those with neurotic, substance use, and organic mental disorders, cancer, and epilepsy; and 3) those with Schizophrenia. Patients in Cluster 1 were taking more than six medicines and had more hospital visits. Within 18 months, 41 participants developed either one or two chronic conditions, most commonly diabetes, hypertension, or thyroid disease.
Cardiometabolic diseases are most commonly clustered with mood disorders. There is a need for blood pressure and sugar measurement in psychiatric clinics and mood disorder screening in cardiac, endocrinology, and primary care clinics.
关于常见的多重疾病共患集群以及患有精神疾病的个体的医疗保健成本的数据匮乏。本研究旨在确定具有临床意义的身心多重疾病共患集群、常见的疾病集群以及在精神科门诊就诊患者的医疗保健利用模式和支出情况。
于2019年2月至7月在精神科门诊收集了18岁及以上患者的数据(n = 500);18个月后收集了非传染性疾病发病率的随访数据。为进行分析,使用两种方法定义发病集群:1)凝聚层次聚类法以识别疾病集群;2)非层次聚类k均值分析以识别患者集群。还计算了这些集群中自我报告的医疗保健成本。
确定了两个疾病集群:使用第一种方法确定的是;1)高血压、糖尿病和情绪障碍;2)神经症性、应激相关和躯体形式障碍以及消化性溃疡病。使用第二种方法确定了三个患者集群:1)患有情绪障碍以及心脏代谢、肌肉骨骼和甲状腺疾病的患者;2)患有神经症性、物质使用和器质性精神障碍、癌症和癫痫的患者;3)患有精神分裂症的患者。第1组患者服用六种以上药物且住院就诊次数更多。在18个月内,41名参与者患上了一种或两种慢性病,最常见的是糖尿病、高血压或甲状腺疾病。
心脏代谢疾病最常与情绪障碍聚集在一起。精神科诊所需要测量血压和血糖,而心脏科、内分泌科和基层医疗诊所需要进行情绪障碍筛查。