Escola Superior de Ciências da Saúde, Brasília, DF, Brazil.
Hospital Materno Infantil de Brasília, Brasília, DF, Brazil.
Rev Paul Pediatr. 2023 Aug 25;42:e2022215. doi: 10.1590/1984-0462/2024/42/2022215. eCollection 2023.
To evaluate severe acute respiratory syndrome surveillance in a pediatric unit.
Descriptive study of reported severe acute respiratory syndrome cases with the detection of respiratory viruses in the nasopharyngeal sample of patients hospitalized between 2013 and 2019, in a reference hospital in the Federal District, Brazil.
A total of 269 children had one or more viruses detected, resulting in 280 viruses, of which 152 (54%) were respiratory syncytial virus. The detection of respiratory syncytial virus was higher during the autumn-winter period. Children´s median age was 6.9 months, 156 (58%) were male, 104 (39%) had comorbidity, 197 (73%) required mechanical ventilation, 241 (90%) received antibiotics, and 146 (54%) oseltamivir. There were 19 (7%) deaths. The median time from symptom onset to sample collection was 5 days and the median time from sample collection to final results was 6 days.
The system needs to reduce the time to deliver results so that inappropriate use of antibiotics and antivirals can be avoided. Moreover, the burden of viral pneumonia was relevant and the system must be flexible enough to include emerging viruses in order to be useful in responding to public health emergencies caused by respiratory viruses.
评估儿科病房中严重急性呼吸综合征的监测情况。
对巴西联邦区一家参考医院 2013 年至 2019 年间住院的患者鼻咽样本中检测到的呼吸道病毒的报告严重急性呼吸综合征病例进行描述性研究。
共有 269 例儿童被检测出一种或多种病毒，共检测到 280 种病毒，其中 152 种（54%）为呼吸道合胞病毒。呼吸道合胞病毒的检出率在秋冬季节较高。儿童的中位年龄为 6.9 个月，156 例（58%）为男性，104 例（39%）存在合并症，197 例（73%）需要机械通气，241 例（90%）接受抗生素治疗，146 例（54%）接受奥司他韦治疗。有 19 例（7%）死亡。从症状出现到采集样本的中位时间为 5 天，从采集样本到得出最终结果的中位时间为 6 天。
该系统需要缩短报告结果的时间，以避免抗生素和抗病毒药物的不当使用。此外，病毒性肺炎的负担很重，该系统必须足够灵活，以纳入新出现的病毒，以便在应对由呼吸道病毒引起的突发公共卫生事件时发挥作用。
Zotero 插件