Tholla Tanusha S, Sawicki Caleigh M, Bhupathiraju Shilpa N
Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, USA.
Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Room 338, 181 Longwood Ave, Boston, MA, 02115, USA.
Curr Atheroscler Rep. 2023 Oct;25(10):643-652. doi: 10.1007/s11883-023-01138-7. Epub 2023 Aug 30.
Cardiovascular disease (CVD) is one of the top comorbidities associated with COVID-19-both pre- and post-infection. This review examines the relationships between COVID-19 infection and cardiovascular health, with a specific focus on diet as an important modifiable risk factor.
Pandemic era studies of individuals battling and recovering from COVID-19 infection suggest a strong link between metabolic diseases, such as CVD, and SARS-CoV-2 infection susceptibility and severity. Other studies also demonstrate how COVID-19 lockdown policies and quarantine recommendations led to drastic lifestyle changes associated with increased CVD risk, such as reduced physical activity and lower diet quality. At the same time, new research is emerging that plant-based diets, which have previously been associated with lower CVD risk, may lower COVID-19 infection rates and severity of symptoms. Diet, COVID-19, and CVD intersect through complex biological mechanisms and related behavioral factors evidenced by clinical trials and epidemiological studies. Diet may be a critical tool for modifying risk of communicable and non-communicable conditions in the post-pandemic world.
心血管疾病(CVD)是与COVID-19感染前和感染后相关的主要合并症之一。本综述探讨了COVID-19感染与心血管健康之间的关系,特别关注饮食作为一个重要的可改变风险因素。
大流行时代对感染COVID-19并正在康复的个体的研究表明,代谢性疾病(如心血管疾病)与SARS-CoV-2感染易感性和严重程度之间存在密切联系。其他研究还表明,COVID-19封锁政策和隔离建议如何导致与心血管疾病风险增加相关的剧烈生活方式改变,如体育活动减少和饮食质量下降。与此同时,新的研究表明,以前与较低心血管疾病风险相关的植物性饮食可能会降低COVID-19感染率和症状严重程度。饮食、COVID-19和心血管疾病通过复杂的生物学机制和相关行为因素相互关联,临床试验和流行病学研究证明了这一点。在大流行后的世界中,饮食可能是改变传染病和非传染病风险的关键工具。