Dawes L G, Aprahamian C, Condon R E, Malangoni M A
Surgery. 1986 Oct;100(4):796-803.
We reviewed 137 patients with colon injury and applied multiple regression analysis to determine the influence of various parameters on colon-related infection. The complications of intra-abdominal abscess, wound infection, and peristomal abscess occurred in 25% of patients. The mortality rate was 3.6%, and four of five late deaths were caused by infection. Multiple regression analysis identified the amount of blood transfused, patient age, number of associated injuries, and injury to the spleen as significantly associated with infection (p less than 0.05). In the absence of these risk factors, the likelihood of infection is low, suggesting that primary repair or resection and anastomosis are safe methods of management for colon injury. When these factors are present, the risk of infection is high, and colostomy is the preferred method of management.
我们回顾了137例结肠损伤患者,并应用多元回归分析来确定各种参数对结肠相关感染的影响。腹腔内脓肿、伤口感染和造口周围脓肿等并发症发生在25%的患者中。死亡率为3.6%,五例晚期死亡中有四例是由感染引起的。多元回归分析确定输血量、患者年龄、合并伤数量和脾脏损伤与感染显著相关(p小于0.05)。在没有这些危险因素的情况下,感染的可能性较低,这表明一期修复或切除吻合术是治疗结肠损伤的安全方法。当存在这些因素时,感染风险较高,结肠造口术是首选的治疗方法。