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用于心脏骤停的视频喉镜检查与直接喉镜检查:临床研究与试验的荟萃分析

Video laryngoscopy and direct laryngoscopy for cardiac arrest: A meta-analysis of clinical studies and trials.

作者信息

Chien Yu-Ta, Ong Jiann-Ruey, Tam Ka-Wai, Loh El-Wui

机构信息

Department of Emergency Medicine, Mennonite Christian Hospital, Emergency Department, Hualien City, Taiwan.

Department of Emergency Medicine, Taipei Medical University Shuang-Ho Hospital, New Taipei City, Taiwan.

出版信息

Am J Emerg Med. 2023 Nov;73:116-124. doi: 10.1016/j.ajem.2023.08.028. Epub 2023 Aug 16.

Abstract

BACKGROUND

Intubation is an essential procedure in cardiopulmonary resuscitation (CPR). We conducted a systematic review and meta-analysis of trials and studies comparing the performance of video laryngoscope (VL) and direct laryngoscope (DL) in endotracheal intubation (ETI) during CPR in cardiac arrest (OHCA) patients.

METHODS

We searched the PUBMED, EMBASE, and Cochrane library databases. We analyzed the first-pass success rate, total intubation time, Cormack-Lehane grade (CL grade), esophageal intubation rate, and dental injury rate among the in-hospital cardiac arrest (IHCA) patients or out-of-hospital cardiac arrest (OHCA) patients. We demonstrated the pooled results of continuous outcomes by mean difference (MD) and dichotomous outcomes by odds ratio (OR), with a 95% confidence interval (CI) using a random-effects model.

RESULTS

We obtained six observational studies and one randomized control trial. The pooled results showed a significant increase in first-pass success rate (OR: 1.86, 95% CI: 1.41, 2.47), Cormack-Lehane (CL) grade (OR: 2.01, 95% CI: 1.59,2.53), and a decrease of esophageal intubation rate (OR: 0.25, 95% CI: 0.08, 0.85) in the VL group compared with DL group. Also, a non-significant decrease in dental injury rate [OR: 0.23, 95% CI: 0.05, 1.08) was observed in the VL group compared with the DL group. There was no statistical difference between the VL and DL groups, although the VL group seemed to have a shorter total intubation time (MD: -15.43, 95% CI: -34.67, 3.81). Types of laryngoscopes were not associated with the rate of ROSC [OR 1.01 (0.95,1.07); P = 0.83]. No differences in survival outcomes were observed between the two approaches.

CONCLUSIONS

Compared to DL, VL was found to be associated with first-pass success and CL grade. We recommend prioritizing VL over DL when performing ETIs for patients with cardiac arrest.

摘要

背景

气管插管是心肺复苏(CPR)中的一项基本操作。我们对比较视频喉镜(VL)和直接喉镜(DL)在心脏骤停(OHCA)患者心肺复苏期间进行气管插管(ETI)性能的试验和研究进行了系统评价和荟萃分析。

方法

我们检索了PUBMED、EMBASE和Cochrane图书馆数据库。我们分析了院内心脏骤停(IHCA)患者或院外心脏骤停(OHCA)患者的首次成功率、总插管时间、Cormack-Lehane分级(CL分级)、食管插管率和牙齿损伤率。我们使用随机效应模型,通过平均差(MD)展示连续结果的汇总结果,通过比值比(OR)展示二分结果的汇总结果,并给出95%置信区间(CI)。

结果

我们获得了六项观察性研究和一项随机对照试验。汇总结果显示,与DL组相比,VL组的首次成功率(OR:1.86,95%CI:1.41,2.47)、Cormack-Lehane(CL)分级(OR:2.01,95%CI:1.59,2.53)显著提高,食管插管率降低(OR:0.25,95%CI:0.08,0.85)。此外,与DL组相比,VL组的牙齿损伤率有非显著性降低[OR:0.23,95%CI:0.05,1.08]。VL组和DL组之间没有统计学差异,尽管VL组的总插管时间似乎更短(MD:-15.43,95%CI:-34.67,3.81)。喉镜类型与自主循环恢复率无关[OR 1.01(0.95,1.07);P = 0.83]。两种方法在生存结果方面没有差异。

结论

与DL相比,发现VL与首次成功和CL分级相关。我们建议在对心脏骤停患者进行ETI时,优先选择VL而非DL。

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