Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Parasites Hosts Dis. 2023 Aug;61(3):310-316. doi: 10.3347/PHD.22172. Epub 2023 Aug 21.
In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor.
在老年患者中，眼弓形体病是葡萄膜炎的最常见病因之一，需要与眼淋巴瘤相鉴别，后者是老年人葡萄膜炎的另一种常见病理类型。高水平的白细胞介素（IL）-10 和 IL-10/IL-6 比值大于 1（>1.0）有助于诊断眼淋巴瘤。在本研究中，我们使用房水样本检测了 4 例 IL-10 水平升高和 IL-10/IL-6 比值大于 1 的眼弓形体病患者。结果表明，眼弓形体病可能与房水中细胞因子水平升高有关。
