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[小母牛甲基对硫磷中毒病例]

[Case of methyl parathion poisoning in heifers].

作者信息

Zhelev V, Belchev L, Nikolaev K, Tilev K

出版信息

Vet Med Nauki. 1986;23(6):12-8.

PMID:3765378
Abstract

A clinical and morphological study was carried out on mass scale poisoning of heifers with methylparathion. Out of a total of 80 animals in a herd 13 heifers died or were forcedly slaughtered within several hours to three days, and other 9 heifers were cured after diagnosing severe methylparathion poisoning. The presence of the preparation was demonstrated chemically in the stomach and intestinal content of the affected animals. The precise lethal dose, however, was not established owing the outbreak of spontaneous poisoning. On the base of literature data and personal investigations it is believed that in the case described the intake of poisonous matter largely surpassed the lethal dose for cattle (20 mg/kg body mass), particularly on the occasion of a peracute course of the disease. Clinically, the intoxication ran its course with troubles on the part of the central and the vegetative nervous systems. Morphologically, there were oedema of the brain and the meninges, oedema and emphysema of the lungs, degeneration processes in the liver and the other parenchymal organs, oedema and hemorrhagic infiltrations in the wall of the rumen, abomasum, and proximal portions of the intestine, and sporadic or numerous hemorrhages in the organs referred to, particularly on the epi- and endo cardium.

摘要

对小母牛大规模甲拌磷中毒进行了临床和形态学研究。在一群共80头牛中,13头小母牛在数小时至三天内死亡或被迫屠宰,另外9头小母牛在被诊断为严重甲拌磷中毒后治愈。在患病动物的胃和肠内容物中通过化学方法证实了该制剂的存在。然而,由于自发中毒的爆发,确切的致死剂量未确定。根据文献资料和个人调查,据信在所描述的病例中,有毒物质的摄入量大大超过了牛的致死剂量(20毫克/千克体重),尤其是在疾病呈超急性病程的情况下。临床上,中毒表现为中枢神经系统和植物神经系统的紊乱。形态学上,有脑和脑膜水肿、肺水肿和气肿、肝脏和其他实质器官的变性过程、瘤胃、皱胃和肠近端壁的水肿和出血性浸润,以及上述器官中散在或大量出血,特别是在心外膜和心内膜上。

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